Publications of the Week Defining the Impact of Mutation Accumulation on Replicative Lifespan in Yeast Using Cancer-Associated Mutator Phenotypes Lee, M.B., et al. | February 18, 2019 Our lab in the Department of Pathology at UW is interested in how cells deal…sciencecityFebruary 18, 2019 Read More
Publications of the Week Development of Decreased-Gluten Wheat Enabled by Determination of the Genetic Basis of lys3a Barley Moehs, C.P., et al. | February 15, 2019 Celiac disease is the most common food-induced enteropathy in humans, with a prevalence of approximately…sciencecityFebruary 15, 2019 Read More
Publications of the Week Merkel Cell Polyomavirus Tumor Antigens Expressed in Merkel Cell Carcinoma Function Independently of the Ubiquitin Ligases Fbw7 and β-TrCP Dye, K.N., et al. | February 13, 2019 Merkel cell polyomavirus (MCPyV) accounts for 80% of all Merkel cell carcinoma (MCC) cases through…sciencecityFebruary 13, 2019 Read More
Publications of the Week Targeting the Perivascular Niche Sensitizes Disseminated Tumour Cells to Chemotherapy Carlson, P., et al. | February 8, 2019 The presence of disseminated tumour cells (DTCs) in bone marrow is predictive of poor metastasis-free…sciencecityFebruary 8, 2019 Read More
Publications of the Week Characterizing the Major Structural Variant Alleles of the Human Genome Audano, P.A., et al. | February 6, 2019 In order to provide a comprehensive resource for human structural variants (SVs), we generated long-read…sciencecityFebruary 6, 2019 Read More
Publications of the Week Basophil-Derived Tumor Necrosis Factor Can Enhance Survival in a Sepsis Model in Mice Science in Seattle | February 4, 2019 Our publication in Nature Immunology revealed how a rare group of white blood cells called basophils play…sciencecityFebruary 4, 2019 Read More
Publications of the Week CIRCling the Wagons to Protect Intestinal Stem Cells Soveg, F., et al. | February 1, 2019 The epithelium of the small intestine is tasked with balancing its role of absorbing nutrients…sciencecityFebruary 1, 2019 Read More
Publications of the Week Chronic TLR7 and TLR9 Signaling Drives Anemia via Differentiation of Specialized Hemophagocytes Akilesh, H.M., et al. | January 30, 2019 Read the Publication This week we profile a recent publication in Science from Dr. Jessica…sciencecityJanuary 30, 2019 Read More
Publications of the Week The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons Daniels, B.P., et al. | January 28, 2019 My lab has been focused on programmed cell death, and on how the immune system…sciencecityJanuary 28, 2019 Read More
Publications of the Week Glycan Targeted Polymeric Antibiotic Prodrugs for Alveolar Macrophage Infections Chen, J., et al. | January 25, 2019 Alveolar macrophages resident in the lung are prominent phagocytic effector cells of the pulmonary innate…sciencecityJanuary 25, 2019 Read More