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DTSTART;TZID=America/Vancouver:20181209T123000
DTEND;TZID=America/Vancouver:20181211T193000
DTSTAMP:20181029T205259Z
CREATED:20181029T205259Z
LAST-MODIFIED:20181029T205259Z
UID:4779-1544358600-1544556600@scienceinseattle.com
SUMMARY:Metabolites as Signaling Molecules
DESCRIPTION:Once thought of merely as byproducts of cellular metabolism\, we now appreciate how metabolites can directly impact a myriad of processes\, from signalling to gene expression\, in cells. Cells adapt metabolism to allow ATP production and the redistribution of carbons to nucleotide\, protein\, and fatty acid syntheses to support their physiological functions. Metabolism can also influence cell state\, with increasing evidence that changes in metabolite levels can affect both pathway regulation and gene expression\, particularly through the effects of these metabolites on chromatin modifications. One example driven by genetic mutations is the role played by “oncometabolites\,” which can impact the activity of enzymes that control epigenetic state. Such crosstalk between metabolism and epigenetics appears to be bi-directional\, with multiple epigenetic enzymes acting as rheostats to readjust metabolism following nutrient changes. More recent studies determined that alterations in the microbiome influence availability of metabolites\, in turn affecting signaling\, cell proliferation\, and chromatin. Lastly\, changes in metabolites with age can impact both Sirtuins and PARP enzymes\, influencing diverse pathways\, including epigenetics and DNA repair. \nThis meeting will bring together scientists studying metabolites and their signaling properties and how they affect many aspects of health\, including aging and cancer. \nTopics: \n\nMetabolite Regulation of Epigenetics and Gene Expression\nMetabolites and Signaling\nMetabolites in Cancer\nMetabolites in Organismal Physiology and Aging\nMetabolites and the Microbiota
URL:https://scienceinseattle.com/event/metabolites-signaling-molecules/
LOCATION:Motif Seattle\, 1415 Fifth Avenue\, Seattle\, WA\, 98101\, United States
ATTACH;FMTTYPE=image/jpeg:https://scienceinseattle.com/wp-content/uploads/sites/4/2018/10/Cell.jpg
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BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20181209T123000
DTEND;TZID=America/Vancouver:20181211T193000
DTSTAMP:20181029T205259Z
CREATED:20181029T205259Z
LAST-MODIFIED:20181029T205259Z
UID:25348-1544358600-1544556600@scienceinseattle.com
SUMMARY:Metabolites as Signaling Molecules
DESCRIPTION:Once thought of merely as byproducts of cellular metabolism\, we now appreciate how metabolites can directly impact a myriad of processes\, from signalling to gene expression\, in cells. Cells adapt metabolism to allow ATP production and the redistribution of carbons to nucleotide\, protein\, and fatty acid syntheses to support their physiological functions. Metabolism can also influence cell state\, with increasing evidence that changes in metabolite levels can affect both pathway regulation and gene expression\, particularly through the effects of these metabolites on chromatin modifications. One example driven by genetic mutations is the role played by “oncometabolites\,” which can impact the activity of enzymes that control epigenetic state. Such crosstalk between metabolism and epigenetics appears to be bi-directional\, with multiple epigenetic enzymes acting as rheostats to readjust metabolism following nutrient changes. More recent studies determined that alterations in the microbiome influence availability of metabolites\, in turn affecting signaling\, cell proliferation\, and chromatin. Lastly\, changes in metabolites with age can impact both Sirtuins and PARP enzymes\, influencing diverse pathways\, including epigenetics and DNA repair. \nThis meeting will bring together scientists studying metabolites and their signaling properties and how they affect many aspects of health\, including aging and cancer. \nTopics: \n\nMetabolite Regulation of Epigenetics and Gene Expression\nMetabolites and Signaling\nMetabolites in Cancer\nMetabolites in Organismal Physiology and Aging\nMetabolites and the Microbiota
URL:https://scienceinseattle.com/event/metabolites-signaling-molecules-2/
LOCATION:Motif Seattle\, 1415 Fifth Avenue\, Seattle\, WA\, 98101\, United States
ATTACH;FMTTYPE=image/jpeg:https://scienceinseattle.com/wp-content/uploads/sites/4/2018/10/Cell.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20181209T123000
DTEND;TZID=America/Vancouver:20181211T193000
DTSTAMP:20181029T205259Z
CREATED:20181029T205259Z
LAST-MODIFIED:20181029T205259Z
UID:26313-1544358600-1544556600@scienceinseattle.com
SUMMARY:Metabolites as Signaling Molecules
DESCRIPTION:Once thought of merely as byproducts of cellular metabolism\, we now appreciate how metabolites can directly impact a myriad of processes\, from signalling to gene expression\, in cells. Cells adapt metabolism to allow ATP production and the redistribution of carbons to nucleotide\, protein\, and fatty acid syntheses to support their physiological functions. Metabolism can also influence cell state\, with increasing evidence that changes in metabolite levels can affect both pathway regulation and gene expression\, particularly through the effects of these metabolites on chromatin modifications. One example driven by genetic mutations is the role played by “oncometabolites\,” which can impact the activity of enzymes that control epigenetic state. Such crosstalk between metabolism and epigenetics appears to be bi-directional\, with multiple epigenetic enzymes acting as rheostats to readjust metabolism following nutrient changes. More recent studies determined that alterations in the microbiome influence availability of metabolites\, in turn affecting signaling\, cell proliferation\, and chromatin. Lastly\, changes in metabolites with age can impact both Sirtuins and PARP enzymes\, influencing diverse pathways\, including epigenetics and DNA repair. \nThis meeting will bring together scientists studying metabolites and their signaling properties and how they affect many aspects of health\, including aging and cancer. \nTopics: \n\nMetabolite Regulation of Epigenetics and Gene Expression\nMetabolites and Signaling\nMetabolites in Cancer\nMetabolites in Organismal Physiology and Aging\nMetabolites and the Microbiota
URL:https://scienceinseattle.com/event/metabolites-signaling-molecules-3/
LOCATION:Motif Seattle\, 1415 Fifth Avenue\, Seattle\, WA\, 98101\, United States
ATTACH;FMTTYPE=image/jpeg:https://scienceinseattle.com/wp-content/uploads/sites/4/2018/10/Cell.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20181210T183000
DTEND;TZID=America/Vancouver:20181210T203000
DTSTAMP:20181126T180522Z
CREATED:20181126T180522Z
LAST-MODIFIED:20181126T180522Z
UID:4970-1544466600-1544473800@scienceinseattle.com
SUMMARY:Women in Bio Annual Holiday Celebration
DESCRIPTION:Join us at The Collective for our Annual Holiday Celebration! WIB-Seattle welcomes you to a merry networking mixer that will start even the chilliest December week off right. We will celebrate the past year\, connect with new and old WIB friends\, and celebrate the season together. Be sure to register early to avoid missing one of our most popular events.
URL:https://scienceinseattle.com/event/women-bio-annual-holiday-celebration/
LOCATION:The Collective\, 400 Dexter Ave N\, Seattle\, WA\, 98109\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20181210T183000
DTEND;TZID=America/Vancouver:20181210T203000
DTSTAMP:20181126T180522Z
CREATED:20181126T180522Z
LAST-MODIFIED:20181126T180522Z
UID:25362-1544466600-1544473800@scienceinseattle.com
SUMMARY:Women in Bio Annual Holiday Celebration
DESCRIPTION:Join us at The Collective for our Annual Holiday Celebration! WIB-Seattle welcomes you to a merry networking mixer that will start even the chilliest December week off right. We will celebrate the past year\, connect with new and old WIB friends\, and celebrate the season together. Be sure to register early to avoid missing one of our most popular events.
URL:https://scienceinseattle.com/event/women-bio-annual-holiday-celebration-2/
LOCATION:The Collective\, 400 Dexter Ave N\, Seattle\, WA\, 98109\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20181210T183000
DTEND;TZID=America/Vancouver:20181210T203000
DTSTAMP:20181126T180522Z
CREATED:20181126T180522Z
LAST-MODIFIED:20181126T180522Z
UID:26327-1544466600-1544473800@scienceinseattle.com
SUMMARY:Women in Bio Annual Holiday Celebration
DESCRIPTION:Join us at The Collective for our Annual Holiday Celebration! WIB-Seattle welcomes you to a merry networking mixer that will start even the chilliest December week off right. We will celebrate the past year\, connect with new and old WIB friends\, and celebrate the season together. Be sure to register early to avoid missing one of our most popular events.
URL:https://scienceinseattle.com/event/women-bio-annual-holiday-celebration-3/
LOCATION:The Collective\, 400 Dexter Ave N\, Seattle\, WA\, 98109\, United States
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