Science in Seattle

Desert Sun Guild's Spring Gala
2022-05-07 18:00 - 23:00 UTC | Michele’s Event Center, 2323 Henderson Loop, Richland, WA, 99354, United States
Dinner, Auction and Dancing. Entertainment by Groove Principal.

Distinguished Seminar: Ilana Witten
2022-05-10 10:30 - 11:30 UTC | Online
Ilana Witten is a professor of neuroscience and psychology at Princeton University. She was first introduced to neuroscience as an undergraduate physics major, when she studied neural coding in the retina with Michael Berry at Princeton. She then moved to Stanford to pursue a PhD in neuroscience, where she worked in the systems neuroscience lab of Eric Knudsen. As a postdoctoral fellow, she worked with Karl Deisseroth in the Department of Bioengineering at Stanford, developing and applying optogenetic tools to dissect the neuromodulatory control of reward behavior in rodents. Since 2012, her lab at the Neuroscience Institute and Department of Psychology at Princeton has focused on understanding the circuitry in the striatum that support reward learning and decision making. She has received multiple awards for her work, including an NIH New Innovator Award, a Mcknight Scholars Award, and the Daniel X Freedman Prize.

DeviceConnect: Novel Delivery Mechanisms for Modern Medicine
2022-05-10 16:00 - 17:30 (America/Vancouver) | Online
The rapid evolution of modern medicine has spurred incredible advancements in vaccine and drug delivery. As the pace of innovation and drug discovery continues to accelerate, medical device R&D organizations have had to keep pace to effectively produce mechanisms to deliver these critical and emerging treatments. In this DeviceConnect, we’ll hear directly from leaders who are innovating on the medical and delivery sides to meet modern needs and patient scenarios.

Biostatistics Seminar Series
2022-05-11 12:00 - 13:00 (America/Vancouver) | Online
The Fred Hutch Biostatistics Program hosts seminars featuring presentations by Fred Hutch and outside scientists to share their latest developments and recent research. Each seminar includes an hour-long presentation and discussion during which speakers showcase their work and findings.
This seminar will be held on Zoom due to the COVID-19 pandemic.
PRESENTER: Min Qian, Ph.D.

“Regularized greedy gradient Q-learning with mobile health applications”

Recent advance in health and technology has made mobile apps a viable approach to delivering behavioral interventions in areas including physical activity encouragement, smoking cessation, substance abuse prevention, and mental health management. Due to the chronic nature of most of the disorders and heterogeneity among mobile users, delivery of the interventions needs to be sequential and tailored to individual needs. We operationalize the sequential decision making via a policy that takes a mobile user’s past usage pattern and health status as input and outputs an app/intervention recommendation with the goal of optimizing the cumulative rewards of interest in an indefinite horizon setting. we propose a regularized greedy gradient Q-learning (RGGQ) method to tackle this estimation problem. The optimal policy is estimated via an algorithm that synthesizes the PGM and the GGQ algorithms, and its asymptotic properties are established.

Frameworks for Brain Cell Type Definition, Ontology, and Nomenclature Workshop: Mapping of Cell Type Data
2022-05-12 08:00 - 14:00 (America/Vancouver) | Online
In this virtual workshop, we will explore best practices for mapping single cell data to reference cell atlases. Mapping single cell data to reference cell atlases is complicated by batch effects between datasets, systematic differences in biological conditions of the samples, limited availability of computational resources, and sharing restrictions on raw data. While our focus is on transcriptomically-defined cell types of the brain, applications in other tissues and in the use of other data modalities will also be considered.

Thursday, May 12, 2022
8am-2pm Pacific Time
REGISTRATION: GENERAL ATTENDEE
General attendees are invited to listen to the full workshop and pose questions to the speakers. Registration is free.
REGISTRATION: DATA CHALLENGE
Data challenge participants will submit preliminary results and have the opportunity to present at the workshop. Participation is free.

Defining and naming cell types is a key problem of contemporary neuroscience. While the problem has preoccupied neuroscientists for over a century, it now has significantly increased attention due to our ability to collect cellular level data in a high-throughput manner. International consortia involved in molecular brain cell classification, including the BRAIN Initiative Cell Census Network (BICCN), the Human Cell Atlas (HCA), and the Human Biomolecular Atlas Program (HuBMAP) are generating and classifying cell types in all organ systems in the human body at a rapid pace. Standards for classification, naming, and data mapping are essential to form a common language of cell types to make sense of these enormous datasets, and to promote understanding between multiple domains, projects, and scientists.
Essential to our understanding of cell types and their functions is to catalog measured transcriptomes of cells belonging to each cell type, and to present this information in the form of comprehensive reference single cell atlases. Much like how reference genomes provide a map for locating the origin of sequencing reads, reference cell atlases can be used to map query cells to potential cell types in the reference atlas in order to rapidly characterize and compare relevant cell phenotypes. Reference atlases ultimately help quantify transcriptional heterogeneity that arises as a result of natural variation, aging, environmental influences, and disease. Large single-cell atlases comprising millions of cells across tissues, organs, donors, developmental stages, and conditions are now being generated by consortia such as the Human Cell Atlas and BICCN to serve as references for smaller-scale studies.
The workshop will include presentations about key state-of-the-art methods and techniques, and a comparison of results obtained by different methods in a hands-on data mapping challenge. To explore these mapping techniques, workshop participants will be provided with data mapping “challenges” to be completed before the workshop. Creative solutions to these challenges will have the opportunity to present to a national audience at the June 6, 2022, BRAIN Initiative Cell Census Network (BICCN) consortium meeting and participate in a published article detailing the challenge results.

Research Roundtable with Drs. Jenn Hadlock and Sam Piekos
2022-05-12 16:00 - 17:00 (America/Vancouver) | Online
The Impact & Outcomes of COVID During Pregnancy
May 12, 2022 at 4:00 PM PT
Register to receive access to this online event.

ISB’s Research Roundtable is a virtual series that is free and open to all. These events are designed for a lay audience and provide opportunities to ask questions directly to our scientists.
Check out our Events Page for more upcoming events.
A link to the event will be emailed to you upon registration. If you have additional questions, please email Audri Hubbard at ahubbard@isbscience.org.

Innovators Network Happy Hour - In Person!
2022-05-12 17:30 - 19:30 (America/Vancouver) | Elysian Taproom, 5410 Airport Way S, Seattle, WA, United States
Join us for iconic PNW brews and science! Meet us at Elysian Taproom in Georgetown to mingle with researchers who are creating immunotherapies, exploring the hidden effects of viruses on our cells, tackling health disparities, bringing HIV vaccines closer to reality, and building technologies that defuse cancer-causing mutations. We’ll break into small groups, and our five researchers will rotate through to share their work and answer questions over beers, wine, cider, and snacks.
After 27 months of virtual events (but who’s counting?), we are thrilled to be hosting this IN-person IN Happy Hour! We have a lot to share, and we cannot wait see you.
This free event is open to the community.

Neurofibromatosis Symposium
2022-05-14 09:00 - 13:00 (America/Vancouver) | Online
Meet various Seattle Children’s Neurofibromatosis (NF) providers from several areas including Neurodevelopment, Orthopedics, Physical Therapy and more. Our providers will give presentations and answer questions, and there will even be raffle prizes!

Date: Saturday, May 14, 2022 9:00 a.m. – 1:00 p.m.
Audience: All Families, All Parents/Caregivers
Contact: Jill Richmond
Instructions: Join by computer/smart phone: https://seattlechildrens.webex.com, ID# 2463 696 7914, password: [REDACTED]
Join by dialing into 1-650-479-3207, access code 2463 696 7914, password: [REDACTED]

Global Oncology Lecture Series
2022-05-16 08:00 - 09:00 (America/Vancouver) | Online
Doug Pyle, Vice President, International Affairs, American Society of Clinical Oncology
Seminar: “Responding to the ‘Slow-motion Catastrophe’: ASCO’s Global Engagement”

Cultivating a Beloved Community
2022-05-16 12:00 - 13:00 (America/Vancouver) | Online
Join us for the Cultivating a Beloved Community public dialogue series on Monday, May 16 from 12 – 1 p.m.
Panelists, employees, and the broader community are invited to engage in dialogue with us around art, health care, and healing within the Black community. Tune in for a powerful discussion.

Featuring

Dr. Paul Buckley

Vice President, Chief Diversity & Inclusion Officer, Fred Hutch
About the Public Art & Community Dialogue Program
Led by the Fred Hutch Office of Diversity, Equity & Inclusion, the Public Art and Community Dialogue program provides an opportunity for employees and the broader community to be in dialogue about community solidarity and our pursuit of equity in research and healthcare. This program will foster ongoing dialogues with marginalized and oppressed communities to inform our commitment to inclusion, and how we represent that commitment in visual form.
Selected artists from underrepresented and minoritized communities will develop public art expressions for Fred Hutch banners and flags that will be informed by these dialogues. These images will reflect the themes, emotions, expressions, history, culture, and aspirations of the affinity communities and the commitments of Fred Hutch to deepen our anti-racist and inclusive efforts in scientific excellence.

World IP Day Symposium
2022-05-17 08:45 - 12:45 (America/Vancouver) | Online
Across the globe, people are stepping up to innovation challenges, using their energy and ingenuity, their curiosity and creativity to steer a course towards a better future. This year, the World Intellectual Property Day 2022’s theme focuses on Innovating for a Better Future. We will explore how innovative, energetic and creative minds are driving positive change specifically around the convergence of life science and IT. Please join to learn more about “The Intersection of Biology and Silicon Valley: What the Future of IP looks like in the age of Biotech and IT Convergence.” We will also have breakout sessions focused on specific topic areas as well as conversations on available USPTO resources.

Registration opens at 8:45 am with a start time of 9:00 am.
Stay tuned for speaker announcements.
