On Saturday night, over 800 people came together at the 2018 Hutch Holiday Gala to celebrate the intersection of data science, technology and life sciences — and its potential to transform cancer prevention, diagnosis and treatment. Led by a $4 million challenge gift from Microsoft, the largest health care–focused philanthropic contribution in the company’s history, Saturday’s black-tie event raised more than $10.4…
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Two Years of Glowing Cells for Science

They started with a handful of cells taken from a volunteer’s skin. The cells were engineered in two different laboratories, first to revert the skin cells back to a nascent state, known as pluripotent stem cells, and then to highlight different parts of the cells with glowing fluorescent labels. Nearly 400 vials are now at home in 17 different countries…
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Researchers at the Allen Institute have uncovered subtle but intriguing differences between a mouse and human neuron of the same kind. The differences they found could have implications for studying human brain disorders or brain therapies in laboratory mice. Looking at living neurons from one region of the cortex, the outermost part of the mammalian brain that is responsible for…
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Clinical Potential of Mass Spectrometry-Based Proteogenomics

Cancer genomics research aims to advance personalized oncology by finding and targeting specific genetic alterations associated with cancers. In genome-driven oncology, treatments are selected for individual patients on the basis of the findings of tumour genome sequencing. This personalized approach has prolonged the survival of subsets of patients with cancer. However, many patients do not respond to the predicted therapies…
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Seattle-based biotech firm Impel NeuroPharma closed its latest round of funding, bringing in $67.5 million to develop treatments for central nervous system disorders, such as migraines and Parkinson’s. This is Impel’s largest fundraising round to date, following a $36 million round in December 2016. Impel is known for its Precision Olfactory Delivery (POD) platform, which sends drugs into the nasal cavity with…
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Study Unveils 40 New Mutations Linked to Colorectal Cancer

A group of colorectal cancer researchers are using the word “milestone” to describe their new genomic research, published today in Nature Genetics. “Milestone is a very good description,” said epidemiologist Dr. Ulrike “Riki” Peters, associate director of the Public Health Sciences Division at Fred Hutchinson Cancer Research Center, and one of the lead authors of the study. “This is very important. It…
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Potential Seen for Tailoring Acute Myeloid Leukemia Treatment

Drug response screening of leukemia stem cells offers clues to relapse and suggests ways to improve patient-specific therapies Advances in rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia (AML). Research on the drug responses of leukemia stem cells may reveal why some attempts to treat are not…
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