We know just by living that our bones and muscles are connected. When we flex our muscles, our bones move with them, while our bones hold our bodies together. We also know that strong bones and muscles are essential for daily functioning and injury prevention.
Our bones and muscles can be connected in other ways too. After we are born, bone and muscle grow in mass until we reach the age of about 30, and then decline in concert. As we age, sarcopenia, a condition of muscle weakness and loss of muscle mass, often occurs in people suffering from osteoporosis, a disease of bone fragility. This condition, known as osteosarcopenia, is known as a hazardous duet because muscle weakness increases risk of falling, which can lead to fractures in already fragile osteoporotic bones.
But the mechanisms that explain how bone and mu
