Celiac disease, like all autoimmune diseases, has no cure. People with the condition must adhere to a strict gluten-free diet or face symptoms like nausea, vomiting, ulcers and intestinal damage. This means cutting out breads, pastas, anything that contains flour and many sauces and seasonings. Living with this condition often means constant anxiety about eating, and makes things like parties…
The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, today announced the clinical investigators and institutions that will lead four NIH HIV clinical trials networks over the next seven years to conduct the innovative, efficient clinical research needed to accelerate progress against the HIV pandemic. NIAID also awarded grants to 35 U.S. and international institutions…
More than 5 million Americans are living with Alzheimer’s disease, and that number is expected to nearly triple by 2050. Alzheimer’s is the sixth leading cause of death in the U.S., yet treatments for it and other forms of dementia are largely ineffective. To date, there have been an estimated 400 trials and experimental Alzheimer’s treatments that have failed, suggesting there is limited…
ElitechGroup MDx submitted a coronavirus test manufactured at its facility in Bothell to the Food and Drug Administration for emergency use authorization, the company announced this week. ElitechGroup’s product is a four-in-one diagnostic test that detects and differentiates the coronavirus from other common flus, such as influenza A and B and respiratory syncytial virus. The test requires a sample from…
Umoja Biopharma raised $53 million to expand development of its CAR T-cell immunotherapy treatments for blood-based and organ-based tumors in adult and pediatric patients. Founded last year, the pre-clinical Seattle-based company says it is taking a new three-step approach to immunotherapy by retooling a patient’s immune system in vivo, or within a living organism, to generate cancer-fighting cells inside the…
While scientists have long studied bacterial infections, less attention has been paid to how the host immune response affects bacterial gene expression in the body. In a just-published paper in PNAS, ISB researchers detailed how the bacterium Salmonella conceals itself from the immune system in a type of host cell called the macrophage. Macrophages are the first responders to Salmonella…
In the largest U.S. study of its kind to date, researchers at Children’s Hospital of Philadelphia (CHOP) and other PEDSnet sites report that of more than 135,000 pediatric patients tested for SARS-CoV-2 in pediatric health systems, 4% tested positive for the virus. However, the researchers also found patients from ethnic minorities, adolescents, patients with history of public insurance, and those…
Iodine has long held a hallowed position in the pantheon of public health. It is a key ingredient in the production of thyroid hormone, an important regulator of growth and intellectual development. But in a cruel twist of fate, it is also dangerously deficient in the natural diets of billions of people around the world, putting them at risk of…
The creators of a scientific search engine have unveiled software that automatically generates one-sentence summaries of research papers, which they say could help scientists to skim-read papers faster. The free tool, which creates what the team calls TLDRs (the common Internet acronym for ‘Too long, didn’t read’), was activated this week for search results at Semantic Scholar, a search engine…
As many as 75 percent of the women in North American experience hot flashes, and many of these women still look to hormone therapy to relieve the surge of hormones, otherwise known as vasomotor symptoms, or VMS. But new research, shared recently at the Annual North American Menopause Society Conference, shows the direction of VMS therapy is turning toward new…