Publications of the Week Characterization of Clonal Dynamics Using Duplex Sequencing in Donor-Recipient Pairs Decades After Hematopoietic Cell TransplantationOshima, M., et al. | January 20, 2025Donor-associated clonal hematopoiesis (CH) has been reported in recipients of allogeneic hematopoietic cell transplantation (HCT);…karnottJanuary 20, 2025 Read More
Publications of the Week Brain-Wide Cell-Type-Specific Transcriptomic Signatures of Healthy Ageing in MiceJin, K., et al. | January 13, 2025Biological ageing can be defined as a gradual loss of homeostasis across various aspects of…karnottJanuary 13, 2025 Read More
Publications of the Week Cellular RNA Interacts with MAVS to Promote Antiviral SignalingGokhale, N., et al. | January 8, 2025RIG-I-like receptors (RLRs) are sensors that detect viral RNA in animal cells. RLRs signal to…karnottJanuary 8, 2025 Read More
Publications of the Week Adjusting for Principal Components Can Induce Collider Bias in Genome-Wide Association StudiesGrinde, K., et al. | January 6, 2025Principal component analysis (PCA) is widely used to control for population structure in genome-wide association…karnottJanuary 6, 2025 Read More
Publications of the Week Type I IFN Induces Long-Chain Acyl-CoA Synthetase 1 to Generate a Phosphatidic Acid Reservoir for Lipotoxic Saturated Fatty AcidsBarnhart, S., et al. | December 18, 2024Long-chain acyl-CoA synthetase 1 (ACSL1) catalyzes the conversion of long-chain fatty acids to acyl-CoAs. ACSL1…karnottDecember 18, 2024 Read More
Publications of the Week Identification and Annotation of Centromeric Hypomethylated Regions with Centromere Dip Region (CDR)-FinderLogsdon, G., et al. | December 17, 2024Centromeres are chromosomal regions historically understudied with sequencing technologies due to their repetitive nature and…karnottDecember 17, 2024 Read More
Publications of the Week Development and Validation of Predictive Models of Early Immune Effector Cell-Associated Hematotoxicity (eIPMs)Liang, E., et al. | December 10, 2024Immune effector cell-associated hematotoxicity (ICAHT) is associated with morbidity and mortality after chimeric antigen receptor…karnottDecember 10, 2024 Read More
Publications of the Week Calcium Dynamics of Skin-Resident Macrophages During Homeostasis and Tissue InjuryLeon, P., et al. | December 3, 2024Immune cells depend on rapid changes in intracellular calcium activity to modulate cell function. Skin…karnottDecember 3, 2024 Read More
Publications of the Week Broadly Inhibitory Antibodies to Severe Malaria Virulence ProteinsReyes, R., et al. | November 27, 2024Malaria pathology is driven by the accumulation of Plasmodium falciparum-infected erythrocytes in microvessels1. This process…karnottNovember 27, 2024 Read More
Publications of the Week Single-Cell Analysis of the Multiple Myeloma Microenvironment After Gamma-Secretase Inhibition and CAR T-Cell TherapyCoffey, D., et al. | November 25, 2024Chimeric antigen receptor (CAR) T-cells and bispecific antibodies (BsAb) targeting B-cell maturation antigen (BCMA) have…karnottNovember 25, 2024 Read More