Publications of the Week Expanding the Human Proteome with Microproteins and Peptideins Deutsch, E., et al. | May 12, 2026 A major scientific drive is to characterize the protein-coding genome, which is a primary basis…karnottMay 12, 2026 Read More
Publications of the Week Host Oxidative Stress Primes Mycobacteria for Rapid Antibiotic Resistance Evolution Pepper-Tunick, E., et al. | May 8, 2026 The rapid emergence of multidrug-resistant Mycobacterium tuberculosis (Mtb) threatens global tuberculosis (TB) control, yet the…karnottMay 8, 2026 Read More
Publications of the Week The Proteomic Landscape and Temporal Dynamics of Human and Mouse Gastruloid Development Garge, R., et al. | May 4, 2026 The embryo establishes a body plan and primes itself for organogenesis during gastrulation. As gastrulation…karnottMay 4, 2026 Read More
Publications of the Week Comprehensive Profiling of Clinically Approved Kinase Inhibitors Reveals Mutation-Specific Inhibitors and Opportunities for Drug Repurposing Saifudeen, M., et al. | May 1, 2026 Protein kinases are central to cell signaling and key drug targets in cancer. To inform…karnottMay 1, 2026 Read More
Publications of the Week Protein Overabundance Is Driven by Growth Robustness Choi, J., et al. | April 28, 2026 Protein expression levels optimize cell fitness: Too low an expression level of essential proteins will…karnottApril 28, 2026 Read More
Publications of the Week Distinct Tissue Niches Contribute to Prostate Tissue-Resident Memory CD8+ T Cell Differentiation and Heterogeneity Takehara, K., et al. | April 21, 2026 The prostate is an important exocrine organ, a barrier tissue of the male reproductive system,…karnottApril 21, 2026 Read More
Publications of the Week Spatial Multi-Omics Unveils the Monoclonal Origin, Neuroendocrine Plasticity, and Microenvironment Niches in Combined Small-Cell Lung Cancer Wang, Z., et al. | April 14, 2026 Combined small-cell lung cancer (cSCLC) is an aggressive subtype of SCLC with mixed histologic components.…karnottApril 14, 2026 Read More
Publications of the Week Functional Dissection of Noncoding Variants Associated with Rheumatoid Arthritis Jajodia, A., et al. | April 8, 2026 Noncoding variants are critical to our understanding of the genetic basis of diseases and disorders…karnottApril 8, 2026 Read More
Publications of the Week A Common 19 BP APOE Enhancer Deletion Is Protective Against Alzheimer’s Disease in African Americans Brutman, J., et al. | March 30, 2026 The APOE-ε4/ε4 genotype is the strongest genetic risk factor for sporadic Alzheimer’s disease, though the…karnottMarch 30, 2026 Read More
Publications of the Week Divergent Effects of a Treg-Selective IL-2 Mutein on Influenza-Specific T Cell Responses Albe, J., et al. | March 25, 2026 Enhancing regulatory T cell (Treg) function offers a compelling therapeutic strategy for autoimmune disease. Engineered…karnottMarch 25, 2026 Read More