Publications of the Week Drosophila Epidermal Cells Are Intrinsically Mechanosensitive and Modulate Nociceptive Behavioral OutputsYoshino, J., et al. | May 20, 2025Somatosensory neurons (SSNs) that detect and transduce mechanical, thermal, and chemical stimuli densely innervate an…sciencecityMay 20, 2025 Read More
Publications of the Week In Vivo Functional Screens Reveal KEAP1 Loss as a Driver of Chemoresistance in Small Cell Lung CancerBrumage, L., et al. | May 15, 2025Exquisitely chemosensitive initially, small cell lung cancer (SCLC) exhibits dismal outcomes owing to rapid transition…karnottMay 15, 2025 Read More
Publications of the Week Enteric Tuft Cell Inflammasome Activation Drives NKp46+ILC3 IL22 via PGD2 and Inhibits SalmonellaChurchill, M., et al. | May 14, 2025To distinguish pathogens from commensals, the intestinal epithelium employs cytosolic innate immune sensors. Activation of…karnottMay 14, 2025 Read More
Publications of the Week Functional and Antigenic Landscape of the Nipah Virus Receptor-Binding ProteinLarsen, B., et al. | May 7, 2025Nipah virus recurrently spills over to humans, causing fatal infections. The viral receptor-binding protein (RBP…karnottMay 7, 2025 Read More
Publications of the Week In Vivo Functional Screens Reveal KEAP1 Loss as a Driver of Chemoresistance in Small Cell Lung CancerBrumage, L., et al. | May 1, 2025Exquisitely chemosensitive initially, small cell lung cancer (SCLC) exhibits dismal outcomes owing to rapid transition…karnottMay 1, 2025 Read More
Publications of the Week Human De Novo Mutation Rates From a Four-Generation Pedigree ReferencePorubsky, D., et al. | April 29, 2025Understanding the human de novo mutation (DNM) rate requires complete sequence information1. Here using five…karnottApril 29, 2025 Read More
Publications of the Week Bioprinted Platform for Parallelized Screening of Engineered Microtissues In VivoO'Connor, C., et al. | April 23, 2025Human engineered tissues hold great promise for therapeutic tissue regeneration and repair. Yet, development of…karnottApril 23, 2025 Read More
Publications of the Week Low Overlap of Transcription Factor DNA Binding and Regulatory TargetsMahendrawada, L., et al. | April 21, 2025DNA sequence-specific transcription factors (TFs) modulate transcription and chromatin architecture, acting from regulatory sites in…karnottApril 21, 2025 Read More
Publications of the Week Longitudinal Single Cell Profiling of Epitope Specific Memory CD4+ T Cell Responses to Recombinant Zoster VaccineWen, X., et al. | April 14, 2025Vaccination leads to rapid expansion of antigen-specific T cells within in the first few days.…karnottApril 14, 2025 Read More
Publications of the Week Individualized Dynamic Risk Assessment and Treatment Selection for Multiple MyelomaMurie, C., et al. | April 10, 2025Individualized treatment decisions for multiple myeloma (MM) patients require accurate risk stratification that accounts for…karnottApril 10, 2025 Read More