UW Medicine Researchers Explore New Approaches to Treating Childhood Leukemia

Acute lymphocytic leukemia (ALL) is the most common type of childhood cancer, representing approximately 25% of cancer diagnoses in children 0-15. More than 3,000 new cases of ALL are diagnosed every year in the United States – and the incidence rate is rising. While the 5-year survival rate has increased significantly since 1975 (from 60% to 90% in patients under…
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The lack of new antibiotics is among the most critical challenges facing medicine. Researchers have been on the hunt for new drugs to combat “superbugs” that cannot be penetrated by current antibiotics. Rather than looking for drugs that forcibly penetrate bacteria, researchers tried a new approach: tricking bacteria into taking up a molecule that looks like food, but wreaks havoc…
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5 Things We (Still) Don’t Know About Cells

Picture one of your cells. If you’re not a biologist, chances are you’re thinking about the fried-egg-reminiscent illustration from your grade school science textbooks. Cells were first discovered more than 350 years ago in the cork tree and understood to be the basic building block of all living beings more than 200 years ago — so we must have cells…
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People who have submitted photos to the #MemoriesInDNA project have selected images of family members, favorite places and tasty food that will be preserved for years in the form of synthetic DNA. Now this collection — which currently contains more than 3,000 images and is still growing — will be headed to the final frontier: space. The Arch Mission Foundation, which creates archives…
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Merck Fellows Share Skills for Drug Discovery

 As part of the prestigious Merck Fellowship for Global Health program, IDRI (Infectious Disease Research Institute) is hosting three Fellows in Seattle for three months to assist IDRI scientists in implementing drug metabolism and pharmacokinetic (DMPK) studies, a critical component of a fast-functioning, productive drug discovery program. The Merck Fellows come from around the world bringing expertise ranging from account…
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The Northwest Genomics Center at the University of Washington in Seattle will become one of three genome centers around the country for the National Institutes of Health All of Us Research Program.  The NIH announced the new genome centers this week. Please see the NIH news release. The All of Us Research Program  is gathering data from participants from many backgrounds to create…
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For angiosperms — or flowering plants — one of the most important decisions facing them each year is when to flower. It is no trivial undertaking. To flower, they must cease vegetative growth and commit to making those energetically expensive reproductive structures that will bring about the next generation. In a paper published Sept. 24 in the journal Nature Plants, an international team…
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Few advances in cancer treatment have gotten as much attention in the past decade as immunotherapies, therapies that use the immune system to fight the disease. Various immunotherapies have wiped out disease in terminal patients and have largely enjoyed success as they emerge on the market. But despite those successes, many patients see their cancer return a few months or years after…
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Silverback Therapeutics, a stealthy biotechnology startup, gave the first glimpse of its technology Wednesday as it announced an additional $37.5 million in funding, bringing its Series A round to a total of $47.5 million. The new funds come from Silverback’s existing investor, healthcare investment company OrbiMed, along with two new investors: Biotech giant Celgene and life sciences investor Alexandria Investment Partners. SEC documents…
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The international trade in elephant ivory has been illegal since 1989, yet African elephant numbers continue to decline. In 2016, the International Union for Conservation of Nature cited ivory poaching as a primary reason for a staggering loss of about 111,000 elephants between 2005 and 2015 — leaving their total numbers at an estimated 415,000. In a paper published Sept. 19 in the journal Science…
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