Seattle Children’s is launching BrainChild with the goal of finding better treatments, or even cures, for children with brain cancer. BrainChild is a series of clinical trials that will treat children whose cancer relapsed using CAR T cells, the promising immunotherapy technology that has already led to revolutionary treatments for blood cancers. The treatments could spell hope for the hundreds…
Dr. Charles Murry is the Woods Professor of Pathology, Bioengineering and Medicine/Cardiology at the University of Washington. He also serves as Director of the UW’s Heart Regeneration Program, with the goal of achieving stem cell-based heart regeneration in patients. Dr. Charles Murry has recently published a paper that used stem cell derived heart cells to treat heart damage in monkeys. It’s…
A clinical trial conducted in six medical centers in the United States has suggested that an operation, laparoscopic fundoplication, to treat abnormal acid gastroesophageal reflux in patients with idiopathic pulmonary fibrosis, or IPF, a fatal lung disease, may slow its progression. A paper on the clinical trial was published Aug. 9 in the medical journal The Lancet Respiratory Medicine. Dr. Ganesh Raghu, a UW…
“Imagine a world where diagnosing Alzheimer’s disease is as simple as getting your blood tested during your annual physical,” writes philanthropist Bill Gates. He’s started a venture to fund development of novel biomarkers, which are measurable signs in the brain and body of the presence of disease proteins: amyloid, tau, and α-synuclein, among others. His dream is one shared by all Alzheimer’s…
Before joining ISB as assistant professor and as our newest faculty member this month, Dr. Wei Wei earned his Ph.D. from Caltech and was a faculty member at UCLA Medical School. Read on for a Q&A with Wei that delves into his research career to date, how research might change over the next decade, and his interests and hobbies when not…
The National Institutes of Health has awarded a $6.5 million, five-year grant to the University of Washington and partner institutions to establish the Center for Reproducible Biomedical Modeling. The center’s primary goal is to develop more effective predictive models of biological systems, which are used in research and medicine. “We are delighted that the NIH has made this award,” said Herbert Sauro,…
Seattle Children’s Research Institute is launching a clinical trial that will examine a new kind of cancer-fighting treatment. The treatment is a type of CAR T immunotherapy, which reprograms a person’s immune cells to find and destroy cancer. CAR T therapies have found early success in blood cancers, including leukemia and lymphoma, but have run into obstacles when it comes…
Scientists have completed a major effort to map the regulatory landscape of the mouse genome at a single-cell resolution. The team applied a special assay that they had previously developed to profile a genomic feature called chromatin accessibility. The researchers were interested in how the DNA winding, wrapping and packaging into what is termed chromatin influences what genetic information is…
More than a dozen area tech and biotech companies are supporting Fred Hutch Obliteride this year to help accelerate the lifesaving work at Fred Hutchinson Cancer Research Center. Amazon, Microsoft, Seattle Genetics, Juno, Blue Nile and Lyft are a few of the companies helping sponsor the event and have rallied large teams of employees to participate and fundraise. Other companies including Adaptive Technologies,…
Five years ago, IDRI (Infectious Disease Research Institute) moved into a state-of-the-art lab at 1616 Eastlake Avenue East, which is owned and operated by Alexandria Real Estate Equities, Inc. (NYSE: ARE), in the heart of Seattle’s growing South Lake Union life sciences hub. Today, the IDRI-Alexandria partnership continues as IDRI is hosts a summer intern from the University of Washington’s…