Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 is a genome-editing technology1,2 that utilizes archaeal and bacterial…
sciencecitySeptember 5, 2018
An Assay for De Novo Kinetochore Assembly Reveals a Key Role for the CENP-T Pathway in Budding Yeast
Chromosome segregation depends on the kinetochore, the machine that establishes force-bearing attachments between DNA and…
sciencecityAugust 31, 2018
Two phase 3 placebo-controlled trials of the CYD-TDV vaccine, evaluated in children aged 2-14 y…
sciencecityAugust 29, 2018
Human influenza virus rapidly accumulates mutations in its major surface protein hemagglutinin (HA). The evolutionary…
sciencecityAugust 24, 2018
The SET1/MLL family of histone methyltransferases is conserved in eukaryotes and regulates transcription by catalyzing…
sciencecityAugust 22, 2018
The influenza virus hemagglutinin (HA) fusion glycoprotein mediates viral entry into host cells through its…
sciencecityAugust 20, 2018
CD8+ T cells respond to signals via the T cell receptor (TCR), costimulatory molecules, and immunoregulatory…
sciencecityAugust 17, 2018
The complexity of microbial communities, combined with technical biases in next-generation sequencing, pose a challenge…
sciencecityAugust 15, 2018
Syphilis research has been severely limited by the necessity to propagate Treponema pallidumin vivo in rabbits. After…
sciencecityAugust 10, 2018
