Adaptive Biotechnologies

Position Overview

Directs a multi-level team of production personnel within the molecular laboratory operation (MLO) at the Seattle facility. Provides scheduling, technical and process expertise to ensure accurate, high-throughput testing. Level of position commensurate with experience applicable to the role.


  • Directs the Associate Director of MLO, with associated oversight of all operational aspects of the molecular laboratory at the Seattle site and responsibility for high-throughput laboratory processing of both clinical samples regulated under CLIA, and research samples under GCLP.
  • Directs the Senior Manager of the Biological Sample team with associated oversight of sample accessioning, and study management at the Seattle site
  • Directs the Manager of Laboratory Analytics, planning and scheduling for the MLO team, supporting the production teams, and the VP MLO & Head CLD with business assessments, specifying and improving tools for sample scheduling to meet turnaround times for all samples and projects, and key planning activities that support scaling and throughput in the laboratory
  • Applies laboratory operations management best practices and tools to analyze current equipment usage and process effectiveness to improve productivity and throughput
  • Provides dashboards and updates to senior management to ensure visibility for key operational metrics and to provide proactive alerts
  • Represents the molecular laboratory operations function on core teams for new products and scaling / sustaining initiatives
  • Champions staff needs and is an advocate to enable job satisfaction and professional development to support staff retention
  • Hires, motivates and mentors staff to ensure a pipeline of supervisory and managerial personnel
  • Delegates appropriately to ensure all work is assigned and completed in a timely manner
  • Define and agree goals and milestones with the managers and staff and ensure communication and alignment to the respective teams. Follow up as appropriate to ensure achievement of goals.
  • Champions, leads and prioritizes key initiatives that impact the MLO function and works collaboratively across a wide range of departments to ensure alignment and effective working relationships with our internal customers and partners
  • Strategically assesses and communicates staffing, space and equipment needs in order to meet operational demands
  • Champions strategic needs to meet goals for operational capacity and throughput, and to ensure accurate result generation within specified lab TAT
  • Reviews new documents, and approves updates to existing laboratory requirement documents (e.g., Analytic Methods (METs), SOPs, and Data QC related documents)
  • Promotes a culture of professionalism where every patient result matters, and alignment with company goals and values
  • Alerts CLD in a timely manner of quality or processing issues that could impact patient testing and ensures the laboratory team complies with applicable regulations

Note: This role does not require CLIA qualifications. All functions that impact CLIA sample processing within this role’s purview have oversight by a Clinical laboratory Director.


  • PhD with 12+ years’ experience, Masters’ degree with 18+ years’ experience, or Bachelors’ degree with 20+ years’ experience; Degrees in scientific discipline or Operations Management.
  • 12+ years of experience directing or managing high-throughput, high-complexity laboratories with increasing level of responsibility
  • Specialized knowledge and experience: Molecular biology techniques (DNA extraction, PCR, Next-generation sequencing [NGS]), laboratory automation, Laboratory information management systems
  • Experience and understanding of CLIA regulations and GCLP requirements
  • Demonstration of the following attributes and skills:
    • Self-motivation and with outstanding organizational skills
    • Ability to perform as an effective team leader
    • Strong communication and interpersonal skills, able to quickly absorb and succinctly communicate critical information relevant to role
    • Proven track record of scaling and process improvement in a high-throughput production environment, experience in lean six sigma is a plus
    • Superior judgment, and integrity
    • Advanced critical thinking and problem-solving skills
    • Ability to collaborate across teams and disciplines
    • Creating a positive and productive culture
    • Upholding clinical laboratory best practices and compliance with applicable regulations

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