The UW/Fred Hutch Center for AIDS Research (CFAR) is delighted to announce this year’s International Infrastructure Awards. The Infrastructure Awards are designed to build capacity for UW-affiliated international HIV research activities. Direct costs are up to $10,000 per project. We are excited to announce that we have chosen the following awardees: Bhavna Chohan, MSc, PhD Clinical Assistant Professor of Global Health, University…
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Washington Research Foundation (WRF) has pledged $100,000 to the Institute for Systems Biology (ISB) to support early-career scientists working on high-risk, high-reward healthcare innovations with a path to commercialization and public benefit. In keeping with ISB’s vision, the goal is the advancement of research that addresses pressing issues in human health. ISB created the Innovator Award Program in 2017 to encourage interdisciplinary collaboration among its…
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An “incredibly dynamic year of change,” a “new hope,” and a “gangbusters” year in which the tech sector will come “roaring back.” Those are some of the phrases used by Pacific Northwest tech, science and business leaders to describe their outlook for 2021 ― offering a sense of optimism as we emerge from an extraordinarily challenging year. Of course, the…
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Processing within the anterior cingulate cortex (ACC) is crucial for the patterning of appropriate behavior, and ACC dysfunction following chronic drug use is thought to play a major role in drug addiction. However, cortical pyramidal projection neurons can be subdivided into two major types (intratelencephalic (IT) and pyramidal tract (PT)), with distinct inputs and projection targets, molecular and receptor profiles,…
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“Of course, we didn’t put Democrats in the vial; we didn’t put Republicans in the vial,” University of Washington’s Dr. Larry Corey writes in a recent COVID-19 Vaccine Matters blog jointly produced by Johns Hopkins University and the UW. While development of vaccines now being distributed to combat COVID-19, the deadly disease caused by the novel coronavirus, are a “remarkable achievement” that demonstrate the…
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A longitudinal study of mild adult cases of COVID-19 showed that a multi-layered immune memory response, specific to the pandemic coronavirus SARS-CoV-2, could be detected in the study blood for at least three months after illness was over. In the project’s laboratory experiments, several of these immune-memory defenses displayed powerful attributes associated with antiviral immunity.  While the lab findings are…
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Skin epithelium can accumulate a high burden of oncogenic mutations without morphological or functional consequences. To investigate the mechanism of oncogenic tolerance, we induced HrasG12V in single murine epidermal cells and followed them long-term. We observed that HrasG12V promotes an early and transient clonal expansion driven by increased progenitor renewal that is replaced with an increase in progenitor differentiation leading to reduced…
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A new class of protein material that interacts with living cells without being absorbed by them can influence cell signaling by binding and sequestering cell surface receptors, a new study shows. This breakthrough could have far-reaching implications for stem cell research and enable the development of new materials designed to modulate the behavior of living systems. The research, which appears…
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Today the Allen Institute’s founding CEO, Allan Jones, Ph.D., announced he will step down after nearly 18 years with the organization. In 2003, Jones joined the Institute in its planning stages, was promoted the next year to lead the science mission, then became the first Chief Executive Officer in 2010. Jones will continue to serve as President and CEO until…
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A  study published this week shows that an infectious injury to a fetus’ lungs can be detected by monitoring for an an increase in specific inflammatory proteins in the amniotic fluid. The study suggests that amniocentesis could be used in women with preterm labor to obtain an in utero  snapshot of fetal lung health. “This gives us a tool to track, and detect this infection…
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