Publications of the Week Coordinated Mis-Splicing of TMEM14C and ABCB7 Causes Ring Sideroblast Formation in SF3B1-Mutant Myelodysplastic Syndrome Clough, C., et al. | December 14, 2021 SF3B1 splicing factor mutations are near-universally found in myelodysplastic syndromes (MDS) with ring sideroblasts, a clonal…dcorriganDecember 14, 2021 Read More
Local News Seagen Announces Updated Results from Pivotal HER2CLIMB Trial Evaluating TUKYSA® (Tucatinib) in Patients with HER2-Positive Breast Cancer with Brain Metastases Seagen | December 13, 2021 Seagen Inc. announced the presentation of new data from exploratory analyses from the pivotal HER2CLIMB…dcorriganDecember 13, 2021 Read More
Local News The Most Influential Scientists, Doctors, and Environmentalists in Seattle Seattle Met | December 13, 2021 Kemi Doll is used to being one of the only—or the only—Black women in a room,…dcorriganDecember 13, 2021 Read More
Publications of the Week Information Flow in the Spatiotemporal Organization of Immune Responses Huang, J., Lyons-Cohen, M., and Gerner, M. | December 10, 2021 Immune responses must be rapid, tightly orchestrated, and tailored to the encountered stimulus. Lymphatic vessels…dcorriganDecember 10, 2021 Read More
Local News Mapping Function: Translating Adaptive Immune System Insights into Diagnostics and Drugs Genetic Engineering & Biotechnology News | December 10, 2021 Adaptive Biotechnologies is ‘scratching the surface’ in its quest to create a disease-by-disease map of…dcorriganDecember 10, 2021 Read More
Publications of the Week Discrete Regulatory Modules Instruct Hematopoietic Lineage Commitment and Differentiation Georgolopoulos, G., et al. | December 9, 2021 Lineage commitment and differentiation is driven by the concerted action of master transcriptional regulators at…dcorriganDecember 9, 2021 Read More
Local News ISB Creates Algorithms to Accelerate Discovery of Efficacious Treatments for Tuberculosis Institute for Systems Biology | December 9, 2021 Tuberculosis (TB) is the world’s second leading infectious disease killer after COVID-19. One-and-a-half million people…dcorriganDecember 9, 2021 Read More
Local News Seattle Children’s Researchers Discover That Nanobodies Could Pack the Biggest Punch against COVID-19 Variants and Resurgence Seattle Children's | December 8, 2021 When the worst pandemic of the century struck, a group of nine Seattle Children’s Research Institute’s…dcorriganDecember 8, 2021 Read More
Publications of the Week Drug Delivery to the Central Nervous System Nance, E., et al. | December 8, 2021 Despite the rising global incidence of central nervous system (CNS) disorders, CNS drug development remains…dcorriganDecember 8, 2021 Read More
Local News Cyrus Biotechnology Announces $18M Financing and Acquisition of Orthogonal Biologics to Form an Integrated Software-Driven Pre-Clinical-Stage Drug Discovery Firm Cyrus Biotechnology | December 8, 2021 Cyrus Biotechnology, Inc., a Seattle-based biotechnology firm with a proprietary software platform for biologics discovery,…dcorriganDecember 8, 2021 Read More