The Andy Hill Cancer Research Endowment (CARE), a public-private partnership that supports cancer research in Washington, today announced grant awards totaling $1.15 million to leading research scientists advancing cancer research in the state. The CARE Breakthrough Research program funds innovative, cross-disciplinary research and multi-institution collaborations that aim to find the next big discovery in cancer research. Grants were awarded to…
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IDRI is partner in a European Union-funded consortium that is focused on demonstrating how advanced computer modelling and simulation can be used to reduce the costs of the clinical trials to test the efficacy of new therapies for tuberculosis. In a step towards that goal, the STriTuVaD consortium recently published a technical report entitled “A Computer Modeling System of the Dynamics…
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Enhancing the Development of Heart Cells Using Materials Derived from Silk

In an exciting breakthrough that may have implications for stem cell-based treatment of heart disease, the lab of Dr. Deok-Ho Kim at the Institute for Stem Cell and Regenerative Medicine (ISCRM) has successfully used silk-based materials to enhance the development of stem-cell derived cardiomyocytes. In a recent study detailed in the Journal of Materials Chemistry, Dr. Kim and his lab…
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‘Let the Cells Tell the Story’

Dr. Kelly Paulson, a Fred Hutchinson Cancer Research Center postdoctoral fellow in the Chapuis Lab, was on the hunt. She was tracking her quarry’s traces and the devastation it left behind. But it stayed just beyond her grasp. Paulson was trying to find the source of a cancer recurrence. The patient’s rare, aggressive skin cancer had responded to immunotherapy for 22 months…
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One of the most complicated parts of your body — your brain — takes decades to come into its own. Human brain development begins before we are born and continues well into late teenage years and even early adulthood. Understanding this long and complex process is no easy feat. In a newly published study, which was itself several years in the…
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Thirteen years ago, the Fred Hutchinson Cancer Research Center spun out a small startup with a mission to help researchers get a handle on all the data that medical devices were generating. That company, LabKey, has since grown from six to 50 employees and counts Merck, MIT and Britain’s public health agency as clients. But the company never strayed far from home, now…
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De novo cardiomyogenesis is limited to ≈1% per year in the adult mammalian heart.1 Whether newly formed cardiomyocytes are derived from division of pre-existing myocytes or from differentiation of resident cardiac progenitor cells is a topic of debate. Cardiac progenitor cells have been posited as a source of endogenous cardiomyocyte renewal and as cells that can be harvested, expanded in vitro,…
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Barbara Stephanus, a longtime donor to Fred Hutchinson Cancer Research Center, has gifted not one but two endowed chairs to support the center’s science: Dr. Denise Galloway, who studies the role of human viruses in cancer development, is the recipient of the Paul Stephanus Memorial Endowed Chair, named in honor of Barbara Stephanus’ late husband, who worked in real estate.…
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Proteins have now been designed in the lab to zip together in much the same way that  DNA molecules zip up to form a double helix.  The technique, whose development was led by University of Washington School of Medicine scientists, could enable the design of protein nanomachines that can potentially help diagnose and treat disease, allow for the more exact engineering of cells and perform a wide…
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