Life Science Washington Institute (LSWI or LSW Institute), a non-profit 501(c)(3) that supports entrepreneurs across Washington with training, mentoring and connections to funders and strategic partners, has been awarded the U.S. Small Business Administration (SBA) Growth Accelerator Fund Grant for the fourth time. Funding from this grant has allowed Life Science Washington Institute to support the Washington Innovation Network (WIN),…
Read More
As a 13-year-old boy, Nir Barzilai would walk with his grandfather and listen to his life story. Barzilai remembers his grandfather looking old – bald with a white ring of hair, obese and slow. His grandfather was the same age Barzilai is today, but looked 20 years older. Today, Dr. Nir Barzilai is a pioneer in longevity and aging research. He…
Read More
Adaptive Biotechnologies Corporation (Nasdaq: ADPT), a commercial stage biotechnology company that aims to translate the genetics of the adaptive immune system into clinical products to diagnose and treat disease, announced today the launch of an enhanced version of its clonoSEQ® B-cell Clonality (ID) report, which will now feature the immunoglobulin heavy chain (IgH) – V mutation status for patients with chronic…
Read More
Colorectal cancer is a major health concern worldwide. Growing evidence for the role of the gut microbiota in the initiation of CRC has sparked interest in approaches that target these microorganisms. However, little is known about the composition and role of the microbiota associated with precancerous polyps. Here, we found distinct microbial signatures between patients with and without polyps and…
Read More
Through blood and other biological samples, ISB scientists have shown they can identify markers for cancer years before diagnosis. This was the topic of a recent Research Roundtable presentation delivered by Dr. Andrew Magis, Director of Data Science in ISB’s Health Data Science Lab. Prior to his current role at ISB, Magis was the Director of Research at Arivale, a…
Read More
Mammalian development is associated with extensive changes in gene expression, chromatin accessibility, and nuclear structure. Here, the authors follow such changes associated with mouse embryonic stem cell differentiation and X inactivation by integrating, for the first time, allele-specific data from these three modalities obtained by high-throughput single-cell RNA-seq, ATAC-seq, and Hi-C. Allele-specific contact decay profiles obtained by single-cell Hi-C clearly…
Read More
BBI Faculty Conversations was joined by BBI member Dr. Taran Gujral, Assistant Professor in the Human Biology Division at the Fred Hutchinson Cancer Research Center.   BBI:  To start, could you tell us a little bit about your background and the focus of your work? Dr. Gujral: I had a very broad education and training in mathematics, cell biology, biochemistry, and…
Read More

Faculty Spotlight: Dr. Katherine Bennett

As part of Healthy Aging Month, UW’s faculty spotlight for September is Dr. Katherine Bennett, assistant professor in the Division of Gerontology and Geriatric Medicine. Originally from Cleveland, Ohio, Bennett graduated medical school from the Ohio State University College of Medicine & Public Health and has been a member of the UW Department of Medicine since her Internal Medicine Residency…
Read More
During embryogenesis, waves of hematopoietic progenitors develop from hemogenic endothelium (HE) prior to the emergence of self-renewing hematopoietic stem cells (HSCs). Although previous studies have shown that yolk-sac-derived erythromyeloid progenitors and HSCs emerge from distinct populations of HE, it remains unknown whether the earliest lymphoid-competent progenitors, multipotent progenitors, and HSCs originate from common HE. In this study, we demonstrate by…
Read More