HDT Bio Corp., a developer of immunotherapies for oncology and infectious diseases, today announced the first healthy volunteer has been dosed in the company’s US Phase 1 clinical trial of its next generation COVID-19 RNA vaccine, HDT-301. The vaccine targets the Beta variant of SARS-CoV-2 and has a demonstrated ability to provide broad protection against multiple variants of the virus that causes COVID-19 and unique cellular immunity compared to existing mRNA vaccines.
“Our Phase 1 trial will enroll vaccinated and unvaccinated people, giving us the ability to evaluate HDT-301 for use as a booster with other vaccines as well as a primary vaccine,” said HDT Bio CEO Steve Reed. “We made the RNA vaccine to code for the Beta variant because preclinical studies have shown when used as a booster a Beta variant vaccine provides people with a broad protection against a range of variants with more sustained protection thanks to the cellular responses elicited. In addition our RNA platform is designed to provide long-lasting immune responses.”
