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Androgen-Regulated Stromal Complement Component 7 (C7) Suppresses Prostate Cancer Growth

By July 5, 2023No Comments

Investigators show that C7 is specifically expressed by the stromal cells in both mouse and human prostates. The expression level of C7 inversely correlates with clinical outcomes in prostate cancer. C7 is positively regulated by androgen signaling in the mouse prostate stromal cells. The androgen receptor directly transcriptionally regulates the mouse and human C7.