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SciShots: A Tree-Like Mouse Lung

By August 10, 2023No Comments

An embryonic lung transforms into a tree-like structure through a developmental process known as branching morphogenesis. How these delicate, complex structures form in a growing animal is still not well understood. Boston University postdoctoral fellow Dr. Ian Kinstlinger, captured the continuous growth of lungs taken from a developing mouse, taking microscope images every three hours to show lung growth over the course of several days. In these images, specialized epithelial cells on the lung’s surface express a green fluorescent protein. Between the branches, black spaces are filled with soft mesenchyme cells, not visible in these images.