There have been several breakthroughs using electrical stimulation to damaged nerves, but they have required surgeries to implant wires and stimulator inside the body. At the University of Washington, they are showing dramatic success with a much less invasive procedure. “In six months’ time, I flew over 150,000 miles. I snorkeled in the Red Sea, sat on the Great Wall…
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Persistent HIV Infection Works a Lot like Cancer, Study Shows

Scientists at Fred Hutchinson Cancer Research Center in Seattle have strengthened the case that HIV, the virus that causes AIDS, may take a page from cancer’s playbook. The research led by Drs. Joshua Schiffer and Dan Reeves has significant implications for strategies to cleanse remaining reservoirs of HIV infection, which, if ever achieved, would amount to a functional cure for HIV. Their study, released…
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Seattle Genetics’ star cancer drug Adcetris has won Food and Drug Administration approval for treatment of a fast-growing type of non-Hodgkin lymphoma. The approval comes after the drug showed better results in patients than the standard treatment for the cancer. This is the first time the FDA has approved a drug for treatment of newly diagnosed peripheral T-cell lymphoma (PTCL), and it…
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Precision Medicine Looks beyond DNA Sequences

Advances in precision medicine are determined, in large part, by the ability to more carefully and completely analyze and understand the genome. This requires new developments in how we look at DNA that go way beyond sequencing data. The new developments in this space promise limitless creativity and versatility, from methods that detect DNA in such small amounts that rare…
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The medical application of cannabis has been a calling card for marijuana legalization advocates for years, although to date there are just two FDA-approved medications on the market containing cannabinoids. However, an exciting licensing agreement between the UW and Pascal Biosciences, Inc. means that a cancer treatment derived from cannabinoids could become FDA-approved as soon as 2019. The agreement, negotiated by the UW’s…
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For the first time, scientists have created from scratch self-assembling protein filaments built from identical protein subunits that snap together spontaneously to form long, helical, thread-like structures. Protein filaments are important to our bodies. In nature, protein filaments play a key role in cell biology. Such filaments are essential components of: The cytoskeletons that give cells their shape and ability to…
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Hutch Science Featured at World’s Premier Cancer Immunotherapy Meeting

This past weekend, researchers from around the world gathered at the 33rd annual meeting of the Society for Immunotherapy of Cancer, or SITC, in Washington, D.C. On the minds of everyone there was one main question: How can we effectively and safely direct the killing powers of the immune system to cure cancers? That’s a question scientists at Fred Hutchinson Cancer…
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Could our blood hold the molecular secrets to a fountain of youth, preventing age-related brain disorders? Are brain aging and Alzheimer’s disease caused by a failure of interconnected systems in our bodies, triggering a domino-like cascade of disease? Can targeting the red blood cells and blood vessels jointly keep our brains healthy and prevent dementia? Three new large-scale, multidisciplinary research…
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You may have agreed to donate your organs when you got your driver’s license. Perhaps you’ve even willed your body to science. But would you give your genome to the federal government? National Institutes of Health officials hope 1 million people will say yes. The NIH is asking for volunteers in a project to sequence the genetic material of a million…
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Seattle’s Fred Hutchinson Cancer Research Center and BGI, a giant in global genomics sciences, announced Tuesday that they are planning to collaborate on projects in a number of areas. The collaboration could see the organizations engage in “mutually agreeable projects in a range of research areas, including cancer genomics, immunology and infectious disease studies,” BGI said in a press release. “We are very…
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