5 Questions with a Cancer Immunotherapy Expert

For more than 40 years, Dr. Phil Greenberg has been working toward a vision: harnessing the power of a patient’s immune system to safely and effectively kill their tumors. When the Fred Hutchinson Cancer Research Center scientist started his career, the idea was far from mainstream. Now, there’s a Nobel Prize, immunotherapies have become standard of care for several cancers, and a constant…
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Finding a fast and inexpensive way to detect specific strains of bacteria and viruses is critical to food safety, water quality, environmental protection and human health. However, current methods for detecting illness-causing strains of bacteria such as E. coli require either time-intensive biological cell cultures or DNA amplification approaches that rely on expensive laboratory equipment. Now, Josh Hihath, an associate professor of…
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A new international collaboration between the Allen Institute for Brain Science, a division of the Allen Institute, and Southeast University in Nanjing, China, is tackling the difficult problem of capturing the entire 3D shape of mouse neurons, cell by cell, from the entire animal’s brain. The new effort, called the SEU-Allen Joint Center for Neuron Morphology or the SEU-Allen Center, is…
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Eric Dishman is a living, breathing advertisement for the ambitious experiment he’s in charge of, the National Institutes of Health’s “All of Us” drive to collect and analyze the genomes of a million Americans. If it weren’t for the fact that he had his genome sequenced seven years ago, he probably would not be living and breathing. Back then, he was struggling…
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What would the world look like if there was a clear path for game-changing innovation to transform global health? And what if that path was faster, more efficient, more reliable – more local – than ever before? Innovation is our best bet to truly bend the curve in global health—to save and improve more lives, eliminate more diseases, and deliver on the…
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The first locally acquired case of West Nile virus in a King County resident has been reported by Public Health — Seattle & King County. The virus is transmitted to humans by mosquitos, and most people who are infected don’t develop any symptoms. But, in rare cases, people can develop a serious illnesses affecting the brain, according to the Centers for Disease Control and Prevention. Justin…
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Metastatic Breast Cancer Research Takes the Stage

The keynote speaker got the flu and the morning sunshine turned to sloppy rain, but hope, health and science continued to shine brightly at the third annual Northwest Metastatic and Lobular Breast Cancer Conference, held Friday and Saturday in Seattle. Created for patients by patients, the conference was facilitated by funding from Komen Puget Sound and a slew of sponsors,…
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For the first time scientists have successfully designed non-local beta-sheet proteins from scratch. These structures will be essential for creating artificial antibodies and active sites for enzymes and ligand-binding proteins, which are critical to many processes in living things. The advance opens the way for custom-designing complex proteins for therapeutics, diagnostics and industrial enzymes, said Enrique Marcos, who with Tamuka…
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Neuroscientists at the Allen Institute have moved one step closer to understanding the complete list of cell types in the brain. In the most comprehensive study of its kind to date, published today on the cover of the journal Nature, the researchers sorted cells from the cortex, the outermost shell and the cognitive center of the brain, into 133 different…
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One of the indisputable leaders in pediatric immunotherapy, Seattle Children’s hospital has begun a new approach to ridding kids of solid tumor cancer. The STRIvE-01 trial is currently recruiting children with solid tumor cancer that either couldn’t be cured or reoccurred, and what makes STRIvE-01 different from the many trials that have come before is that it targets solid tumors.…
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