Alder BioPharmaceuticals has raised $170 million in a stock offering and is ramping up operations after filing an FDA application for eptinezumab, a therapy for patients with chronic migraines. Alder CEO Bob Azelby said the publicly-traded company is using the funds to invest in its supply chain, human resources, and IT and financial infrastructure. It also plans to build out a commercial representative…
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How Seattle Can Disrupt Tuberculosis

A major report recently published by the medical journal The Lancet finds that a tuberculosis-free world is possible. While TB is not an issue that many in Seattle think about, many of the city’s leading institutions are actually doing a tremendous amount to reduce the 4,400 deaths from tuberculosis that occur each and every day. TB is a contagious, potentially fatal infectious disease that…
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A New Technique to Make Beating Human Heart Cells Glow

Allen Institute for Cell Science researchers have developed a new technique that will enable better understanding of human heart muscle cells. The method, described in a study published April 4 in the journal Stem Cell Reports, lays the groundwork for possible future studies of genetic cardiac defects and provides a key marker that could benefit cardiac regenerative medicine research. The method, known…
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Meet PNRI Scientist: Aimée Dudley

Aimée Dudley doesn’t just want to be a scientist, she has to be a scientist. At least that is what her lab colleagues at PNRI say. Aimée Dudley, PhD “I’ve wanted to be a scientist since I was three years old,” says Aimée. “I like challenges and the thrill of discovering something no one knew before – especially answers to questions that have stumped researchers…
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Each year at least 2 million Americans are infected with bacteria that cannot be treated with antibiotics, and at least 23,000 of these people die, according to the Centers for Disease Control. These bacteria can end up in our water, which is why we use disinfectants to kill or stop them from growing to treat both waste and drinking water. But…
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It’s possible to prod immune cells to attack and kill pancreatic cancer cells, according to a report from scientists at the University of Washington School of Medicine and the Fred Hutchinson Cancer Research Center in Seattle.  Their findings challenge the commonly held view that pancreatic cancer does not elicit an immune system response that is robust enough for immunotherapy to be effective. “The failures…
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In order to optimize our health, live into our 90s and effectively deal with chronic diseases, Dr. Lee Hood says we need to adopt 21st century health care. Hood was speaking to an audience of 75 people Monday night at a Town Hall Seattle panel discussion focusing on the future of health. 21st century health care, he said, will optimize…
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