The power of mitochondrial science has the potential to unlock new solutions for heart failure, according to a working group co-chaired by researchers at the University of Washington School of Medicine and Boston University School of Medicine and convened by the National Heart Lung and Blood Institute at the National Institutes of Health.  This common chronic condition, in which the…
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ElevateBio has founded HighPassBio to advance T-cell immunotherapies based on research from the Fred Hutchinson Cancer Research Center. HighPassBio starts life with a phase 1 leukemia cell therapy and the support of a founder that recently raised $150 million to build a portfolio of startups. The story of HighPassBio begins at Fred Hutch, where doctors including Marie Bleakley and Robson Dossa worked…
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Tremendous advances have recently been made in the field of biotechnology. This is a relatively new industry and several companies are working towards unlocking the secrets of the immune system of the body and finding correlations that will aid in the improvement of health and the prevention and cure for certain diseases. This is a broad and still wide-open field.…
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Improved Method for Converting Stem Cells Into Pancreatic Islet Progenitor Cells

Type 1 diabetes is a disease that occurs when the immune system attacks and kills the cells that produce insulin in the pancreas, known as beta-cells. People living with type 1 diabetes require daily injections of insulin to survive and are at risk of both life-threatening hypoglycemia (low blood sugar) and lifelong cardiovascular and neurological health complications that include increased…
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A new monoclonal antibody has been shown to impede the fusion machinery henipaviruses use to merge with the membrane of cells they are attempting to breach. The antibody halts the attack by blocking membrane fusion and the injection of the viral genome into the host cell. The researchers said they hope that these types of laboratory discoveries will pave the…
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Seattle startup SEngine Precision Medicine has raised $5.1 million in fresh funding as it looks to commercialize a platform that can match cancer patients to the right drug and aid in drug discovery. The Series A round was led by the Bangarang Group along with other unnamed investors. Since every patient’s cancer is unique, it’s important to know which drug or drug…
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Genome editing means CRISPR to most people. Yet methods using zinc-finger nucleases, transcription activator-like effector nucleases (TALENs), and meganucleases have their own unique strengths. All of these techniques rely on cellular DNA–repair mechanisms. Options that don’t—base editing, epigenetic editing, and site-specific recombinases—offer further advantages. How did “genome editing” become a household phrase so quickly? This question, posed by Jerel Davis…
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The National Institutes of Health has awarded $20 million to fund five additional hubs designed to speed up the translation of biomedical discoveries into commercially viable diagnostics, devices, therapeutics, and tools to improve patient care and enhance health. The newly selected Research Evaluation and Commercialization Hubs (REACH) expand a national network of proof-of-concept centers that links 34 academic institutions developing best practices…
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OpenScope is now open for round two. The Allen Institute’s “shared observatory” for neuroscience has selected three new research projects to pursue this year, following a successful launch of the program with three inaugural projects in 2018. The new projects will explore how flashing light might alleviate symptoms of Alzheimer’s disease, how the visual system distinguishes different types of motion,…
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