A new lens on visual neurons is laying the groundwork for a more complete “family tree” of the mammalian brain. A team of researchers from the Allen Institute for Brain Science, a division of the Allen Institute, published a study — the largest of its kind to date — in the journal Cell today revealing a new categorization of mouse neurons that…
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A Seattle-based biotech company is working on a new way to identify people who have successfully recovered from COVID-19, which may be a key step to overcoming the virus as a nation. The company is Adaptive Biotechnologies, which researches the adaptive immune system in order to develop products that can diagnose or treat diseases. On Tuesday, the company reported its financial results of Q3.…
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Drug delivery is a recurring conundrum in cancer treatment. Scientists have developed many anti-cancer therapeutics. But those drugs often harm healthy tissues, and drugs can even break down in the bloodstream before reaching the tumor site. Anti-cancer drugs can last longer if dissolved in certain chemical solutions, but many come with potentially toxic side effects.   UW professor Miqin Zhang.Matt…
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A collaboration to share data between top Pacific Northwest cancer research groups has announced its first three projects, focused on genetic analysis for monitoring breast cancer; interactions between gut bacteria and cancer drugs; and machine learning for identifying types of cancers. The Cascadia Data Alliance is tackling initiatives that tease out the unique attributes of cancers and how they behave in individual…
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Janssen Phase 3 COVID-19 Vaccine Trial to Begin at KPWHRI

KPWHRI will soon enroll volunteers in a phase 3 clinical trial to evaluate a COVID-19 vaccine made by Janssen Pharmaceutical Companies of Johnson & Johnson. Sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), this is the second phase 3 COVID-19 vaccine trial to be conducted at KPWHRI, which is also testing a vaccine co-developed by Moderna, Inc. and NIAID. KPWHRI…
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Unrelated mutations, when present in the blood, can lead to false positive results in men with advanced prostate cancer who are undergoing liquid biopsies.  Such tests, which look for variants in the cell-free DNA that tumors shed into the blood plasma, help determine suitable treatment options. “You can actually measure what’s happening with a patient’s tumor by taking a blood…
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An innovative nanoparticle vaccine candidate for the pandemic coronavirus produces virus-neutralizing antibodies in mice at levels 10 times greater than is seen in people who have recovered from COVID-19 infections. Designed by scientists at the University of Washington School of Medicine in Seattle, the vaccine candidate has been transferred to two companies for clinical development. Compared to vaccination with the…
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Sana Biotechnology, Inc. (Sana), focused on creating and delivering engineered cells as medicines, announced today the acquisition of Oscine Corp., a company developing potentially curative or disease modifying cell therapies for diseases of the brain and central nervous system (CNS). The combination will integrate Oscine’s glial progenitor cell program and underlying technologies together with Sana’s broader platform and programs. Terms of…
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A major scientific effort is underway to characterize the proteins in the cerebrospinal fluid to improve diagnostics and clinical monitoring assays, and discover potential therapies, for Alzheimer’s disease. Several research labs at the University of Washington School of Medicine and Stanford University are pooling their protein science expertise in this program.  Their area – proteomics — is the large-scale analysis…
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Dr. Anna Wald, a clinical virologist who built a career at Fred Hutchinson Cancer Research Center and the University of Washington as a leading expert in chronic infections, will be honored by her peers on Oct. 22 when she delivers the John F. Enders Lecture at the nation’s premier gathering of infectious disease scientists. The meeting, known as IDWeek, is hosted…
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