Studies in the lab of Estelle Bettelli, PhD, at Benaroya Research Institute (BRI) demonstrate that disease modifying therapies (DMTs) used to treat individuals with multiple sclerosis significantly change immune responses generated by COVID-19 vaccines. Data from these studies could inform best approaches against COVID-19, not only for people with autoimmune diseases or those who are immunocompromised, but for everyone. The…
Read More
A COVID-19 vaccine developed at the University of Washington School of Medicine has proven safe and effective in late-stage clinical testing. SK bioscience, the company leading the vaccine’s clinical development, will seek authorization for its use in South Korea within the month. The Seattle scientists behind the new vaccine sought to create a ‘second-generation’ vaccine for COVID-19 that is safe,…
Read More
Thoughts, memories, sensations — why are we still in the dark about how they work? Is your brain like a computer? An old-timey telephone switchboard? A dense urban landscape? These are all common analogies for the brain, but most who use them know they are wholly imperfect comparisons. We humans thrive on metaphor and succinct stories, but our brains themselves…
Read More

Rotory Proteins Designed from Scratch

IPD researchers report in Science the design of rotary devices made from custom proteins. These microscopic “axles” and “rotors” come together to form spinning assemblies, rather than being locked in just one orientation. Such mechanical coupling is a key feature of any machine. The new axle-rotor devices — which are each about a billion times smaller than a poppy seed…
Read More
Lumen Bioscience, a clinical-stage biotechnology company developing biologic drugs for highly prevalent diseases, today announced clinical development progress for LMN-201, an investigational orally delivered cocktail to treat and prevent C. difficile infection (CDI). Achievements include FDA clearance of a planned Phase 2 study of LMN-201 and successful completion of a Phase 1 first-in-human study, which validated drug delivery of enteric capsules into the gut. LMN-201…
Read More
What if we could combine technology and medicine to boost the body’s natural ability to fight off life-threatening diseases like cancer — without patients having to undergo harsh treatments like chemotherapy and radiation? Ambitious questions like this are at the forefront of an innovative research collaboration at UW Medicine, created by Hannele Ruohola-Baker, PhD, the associate director of the Institute…
Read More
Seagen Inc. (Nasdaq: SGEN) today announced plans to build a new facility in Everett, Washington, to expand the company’s biomanufacturing capacity and enable the company greater control and flexibility over the production of its medicines to treat cancer. The 270,000-square-foot facility will be built north of the company’s U.S. headquarters in Bothell, Washington. Seagen expects to have the facility operational…
Read More
Judges selected UW Bioengineering team Believe Sleeve to move on to the final Investment Round in this year’s Dempsey Startup Competition, hosted by the UW Foster School’s Buerk Center for Entrepreneurship. The Believe Sleeve team is developing a personalized device to speed relief to the 100 million people worldwide who suffer from phantom limb pain following an amputation. Currently, there is…
Read More
An international consortium of scientists has launched a new effort to create a reference genome that captures the genetic diversity of all the peoples of the world. The researchers describe the initiative, called the Human Pangenome Project, in a paper published Wednesday, April 20, in the journal Nature. “The goal is to collect, organize and make accessible a representation of all the…
Read More