Publications of the Week Uncovering and Resolving Challenges of Quantitative Modeling in a Simplified Community of Interacting Cells Hart, S.F.M., et al. | March 15, 2019 Quantitative modeling is useful for predicting behaviors of a system and for rationally constructing or…sciencecityMarch 15, 2019 Read More
Publications of the Week The Hypothalamic Arcuate Nucleus-Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1 Brown, J.M., et al. | March 13, 2019 In rodent models of type 2 diabetes (T2D), sustained remission of diabetic hyperglycemia can be…sciencecityMarch 13, 2019 Read More
Publications of the Week Divergent Medial Amygdala Projections Regulate Approach-Avoidance Conflict Behavior Miller, S.M., et al. | March 11, 2019 Avoidance of innate threats is often in conflict with motivations to engage in exploratory approach…sciencecityMarch 11, 2019 Read More
Publications of the Week Human and Extracellular DNA Depletion for Metagenomic Analysis of Complex Clinical Infection Samples Yields Optimized Viable Microbiome Profiles Nelson, M.T., et al. | March 8, 2019 Metagenomic sequencing is a promising approach for identifying and characterizing organisms and their functional characteristics…sciencecityMarch 8, 2019 Read More
Publications of the Week The Response to Lymphodepletion Impacts PFS in Aggressive Non-Hodgkin Lymphoma Patients Treated with CD19 CAR-T Cells Hirayama, A.V., et al. | March 4, 2019 Factors associated with durable remission after CD19 chimeric antigen receptor (CAR)-modified T cell immunotherapy for…sciencecityMarch 4, 2019 Read More
Publications of the Week Targeting NOTCH Activation in Small Cell Lung Cancer through LSD1 Inhibition Augert, A., et al. | March 1, 2019 My lab is focused on understanding small cell lung cancer (SCLC), an extremely aggressive and…sciencecityMarch 1, 2019 Read More
Publications of the Week Factors Associated with Durable EFS in Adult B-Cell ALL Patients Achieving MRD-Negative CR after CD19 CAR-T Cells Hay, K.A., et al. | February 27, 2019 Autologous T cells engineered to express a CD19-specific chimeric antigen receptor (CAR) have produced impressive…sciencecityFebruary 27, 2019 Read More
Publications of the Week Integrated Functional Genomic Analysis Enables Annotation of Kidney Genome-Wide Association Study Loci Sieber, K.B., et al. | February 25, 2019 The Akilesh laboratory studies genome organization and function in the kidney. The kidney filter (glomerulus)…sciencecityFebruary 25, 2019 Read More
Publications of the Week An Antigenic Atlas of HIV-1 Escape from Broadly Neutralizing Antibodies Distinguishes Functional and Structural Epitopes Dingens, A.S., et al. | February 21, 2019 Anti-HIV broadly neutralizing antibodies (bnAbs) have revealed vaccine targets on the virus’s envelope (Env) protein…sciencecityFebruary 21, 2019 Read More
Publications of the Week Defining the Impact of Mutation Accumulation on Replicative Lifespan in Yeast Using Cancer-Associated Mutator Phenotypes Lee, M.B., et al. | February 18, 2019 Our lab in the Department of Pathology at UW is interested in how cells deal…sciencecityFebruary 18, 2019 Read More