Publications of the Week A Bifunctional Role for the UHRF1 UBL Domain in the Control of Hemi-Methylated DNA-Dependent Histone Ubiquitylation DaRosa, P.A., et al. | November 23, 2018 This publication reports on the structural mechanism by methylated CpG motifs are maintained following DNA…sciencecityNovember 23, 2018 Read More
Publications of the Week Oncogenic Activation of PI3K Induces Progenitor Cell Differentiation to Suppress Epidermal Growth Zhe, Y., et al. | November 21, 2018 Our recent work discovered stem cell differentiation as the primary block to oncogene-driven clonal expansion…sciencecityNovember 21, 2018 Read More
Publications of the Week h-Channels Contribute to Divergent Intrinsic Membrane Properties of Supragranular Pyramidal Neurons in Human Versus Mouse Cerebral Cortex Kalmbach, B.E., et al. | November 19, 2018 Human and rodent brains are clearly different in terms of size and complexity. Yet, how…sciencecityNovember 19, 2018 Read More
Publications of the Week Dormant Tumor Cells, Their Niches and the Influence of Immunity Goddard, E.T., et al. | November 15, 2018 Despite increased focus on the clinical relevance of dormant metastatic disease, our understanding of dormant…sciencecityNovember 15, 2018 Read More
Publications of the Week De Novo Design of a Non-Local β-Sheet Protein with High Stability and Accuracy Marcos, E., et al. | November 13, 2018 Natural proteins evolved over billions of years to solve biology’s most complex problems. But we…sciencecityNovember 13, 2018 Read More
Publications of the Week Parabrachial CGRP Neurons Establish and Sustain Aversive Taste Memories Chen, J.Y., et al. | November 9, 2018 Food aversions develop when the taste of a novel food is associated with sickness, which…sciencecityNovember 9, 2018 Read More
Publications of the Week A Biobank of Patient-Derived Pediatric Brain Tumor Models Brabetz, S., et al. | November 5, 2018 Our team focuses on pediatric brain tumor therapeutics and the discovery of novel peptide therapeutics…sciencecityNovember 5, 2018 Read More
Publications of the Week Automated Quantification of Bioluminescence Images Klose, A.D. and Paragas, N. | November 2, 2018 We developed a computer-aided analysis tool for quantitatively determining bioluminescent reporter distributions inside small animals.…sciencecityNovember 2, 2018 Read More
Publications of the Week Therapeutic Strategies Targeting Connexins Laird, D.W. and Lampe, P.D. | October 31, 2018 The connexin family of channel-forming proteins is present in every tissue type in the human…sciencecityOctober 31, 2018 Read More
Publications of the Week Glutamatergic Facilitation of Neural Responses in MT Enhances Motion Perception in Humans Schallmo, M.P., et al. | October 29, 2018 Our paper shows how brain chemistry relates to neural responses, and ultimately to how people…sciencecityOctober 29, 2018 Read More