Publications of the Week A Plant-Responsive Bacterial-Signaling System Senses an Ethanolamine Derivative Coutinho, B.G., et la. | September 28, 2018 The research in the Greenberg laboratory focuses on the emerging field of sociomicrobiology – the…sciencecitySeptember 28, 2018 Read More
Publications of the Week Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome Cacchiarelli, D., et al. | September 27, 2018 Cellular reprogramming through manipulation of defined factors holds great promise for large-scale production of cell…sciencecitySeptember 27, 2018 Read More
Publications of the Week Activated PIK3CD Drives Innate B Cell Expansion yet Limits B Cell-Intrinsic Immune Responses Wray-Dutra, M.N., et al. | September 24, 2018 Activated PI3K-delta syndrome (APDS) is an immunodeficiency caused by gain-of-function mutations in PIK3CD. This disease…sciencecitySeptember 24, 2018 Read More
Publications of the Week Receptive Field Center-Surround Interactions Mediate Context-Dependent Spatial Contrast Encoding in the Retina Turner, M.H., et al. | September 20, 2018 Antagonistic receptive field surrounds are a near-universal property of early sensory processing. A key assumption…sciencecitySeptember 20, 2018 Read More
Publications of the Week Chemical Cross-Linking with Mass Spectrometry: A Tool for Systems Structural Biology Chavez, J.D. and Bruce, J.E. | September 18, 2018 Biological processes supporting life are orchestrated by a highly dynamic array of protein structures and…sciencecitySeptember 18, 2018 Read More
Publications of the Week Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination Cohen, S.B., et al. | September 14, 2018 Mycobacterium tuberculosis (Mtb) infection is initiated in the distal airways, but the bacteria ultimately disseminate to…sciencecitySeptember 14, 2018 Read More
Publications of the Week Human T Cell Receptor Occurrence Patterns Encode Immune History, Genetic Background, and Receptor Specificity DeWitt, W.S., et al. | September 10, 2018 High-throughput DNA sequencing has enabled deep profiling of the set of receptors that T and…sciencecitySeptember 10, 2018 Read More
Publications of the Week Cas9 Immunity Creates Challenges for CRISPR Gene Editing Therapies Crudele, J.M., et al. | September 5, 2018 Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 is a genome-editing technology1,2 that utilizes archaeal and bacterial…sciencecitySeptember 5, 2018 Read More
Publications of the Week Early Cellular Innate Immune Responses Drive Zika Viral Persistence and Tissue Tropism in Pigtail Macaques O'Connor, M.A., et al. | September 3, 2018 The immunological and virological events that contribute to the establishment of Zika virus (ZIKV) infection…sciencecitySeptember 3, 2018 Read More
Publications of the Week An Assay for De Novo Kinetochore Assembly Reveals a Key Role for the CENP-T Pathway in Budding Yeast Lang, J., et al. | August 31, 2018 Chromosome segregation depends on the kinetochore, the machine that establishes force-bearing attachments between DNA and…sciencecityAugust 31, 2018 Read More