Publications of the Week Intratumoral Three-Cell-Type Clusters Are a Conserved Feature of Endogenous Antitumor Immunity Damle, S., et al. | February 17, 2026 Effective antitumor immunity ultimately depends on the priming and activation of tumor-specific cytotoxic CD8+ T…karnottFebruary 17, 2026 Read More
Publications of the Week Predicting Epistasis Across Proteins by Structural Logic Tang, M., et al. | February 11, 2026 Epistatic interactions present a major challenge in accurate genotype–phenotype correlation. Here, we combined high-throughput yeast…karnottFebruary 11, 2026 Read More
Publications of the Week DUX4-Induced Hsatii Rna Accumulation Drives Protein Aggregation, Impacting RNA Processing Pathways Arends, T., et al. | February 2, 2026 RNA-driven protein aggregation leads to cellular dysregulation and contributes to the development of diseases and…karnottFebruary 2, 2026 Read More
Publications of the Week Dendritic Cells Regulate the Innate-Adaptive Balance in Lymph Nodes for Optimal Host Defense Huang, J., et al. | January 30, 2026 Lymph nodes (LNs) enable innate defense to limit pathogen dissemination while also driving adaptive immunity.…karnottJanuary 30, 2026 Read More
Publications of the Week Calcineurin Depletion Coincides with Phosphorylated TDP-43 Deposition in a Mouse Model of ALS/FTLD-TDP Waldherr, S., et al. | January 27, 2026 Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD-TDP) exhibit predominantly cytoplasmic phosphorylated inclusions of…karnottJanuary 27, 2026 Read More
Publications of the Week Machine Learning Models Predict Long COVID Outcomes Based on Baseline Clinical and Immunologic Factors Jayavelu, N., et al. | January 23, 2026 The post-acute sequelae of SARS-CoV-2 (PASC), also known as long COVID, remain a significant health…karnottJanuary 23, 2026 Read More
Publications of the Week The Ubiquitin Ligase KLHL6 Drives Resistance to CD8+ T Cell Dysfunction Cheng, H., et al. | January 22, 2026 The multifaceted dysfunction of tumour-infiltrating T cells, including exhaustion and mitochondrial dysfunction, remains a major…karnottJanuary 22, 2026 Read More
Publications of the Week Niche-Derived Semaphorin 4A Safeguards Functional Identity of Myeloid-Biased Hematopoietic Stem Cells Toghani, D., et al. | January 13, 2026 Somatic stem cell pools comprise diverse, highly specialized subsets whose individual contribution is critical for…karnottJanuary 13, 2026 Read More
Publications of the Week An Alveolar Macrophage-Targeted Ciprofloxacin Polymeric Prodrug Improves Survival in a Murine Model of Klebsiella pneumoniae Pneumonia López, C., et al. | January 5, 2026 Klebsiella pneumoniae is a leading cause of both hospital- and community-acquired pneumonia. Nanomaterials have the…karnottJanuary 5, 2026 Read More
Publications of the Week Identification of AMOTL2 as an Antiviral Factor That Enhances the Human Type I Interferon Response Against Zika Virus Willcox, A., et al. | December 15, 2025 Zika virus (ZIKV) can cause severe disease, especially in infants who are infected with the…karnottDecember 15, 2025 Read More