Publications of the Week Niche-Derived Semaphorin 4A Safeguards Functional Identity of Myeloid-Biased Hematopoietic Stem Cells Toghani, D., et al. | January 13, 2026 Somatic stem cell pools comprise diverse, highly specialized subsets whose individual contribution is critical for…karnottJanuary 13, 2026 Read More
Publications of the Week An Alveolar Macrophage-Targeted Ciprofloxacin Polymeric Prodrug Improves Survival in a Murine Model of Klebsiella pneumoniae Pneumonia López, C., et al. | January 5, 2026 Klebsiella pneumoniae is a leading cause of both hospital- and community-acquired pneumonia. Nanomaterials have the…karnottJanuary 5, 2026 Read More
Publications of the Week Identification of AMOTL2 as an Antiviral Factor That Enhances the Human Type I Interferon Response Against Zika Virus Willcox, A., et al. | December 15, 2025 Zika virus (ZIKV) can cause severe disease, especially in infants who are infected with the…karnottDecember 15, 2025 Read More
Publications of the Week The Placental Transcriptome Serves as a Mechanistic Link Between Prenatal Phthalate Exposure and Placental Efficiency Parenti, M., et al. | December 8, 2025 Prenatal exposure to phthalates, pervasive endocrine-disrupting chemicals, has been linked to child health outcomes, including…karnottDecember 8, 2025 Read More
Publications of the Week Targeting FZD6 Creates Therapeutically Actionable Vulnerabilities for Advanced Prostate Cancer Li, Y., et al. | December 4, 2025 Wnt signaling is a complex pathway consisting of numerous ligands and frizzled (FZD) receptors. These…karnottDecember 4, 2025 Read More
Publications of the Week Drug Screening in 3D Microtumors Reveals DDR1/2-MAPK12-GLI1 as a Vulnerability in Cancer-Associated Fibroblasts Nishida-Aoki, N., et al. | November 28, 2025 Interactions between cancer cells and surrounding stromal cells are critical for tumor biology and treatment…karnottNovember 28, 2025 Read More
Publications of the Week Prostate-Specific Membrane Antigen Positron Emission Tomography/Computed Tomography Imaging as a Precision Diagnostic at Prostate Cancer Recurrence After Radical Prostatectomy: Modeling Long-Term Survival Gogebakan, K., et al. | November 20, 2025 Prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA-PET/CT) is affecting the management of patients with…karnottNovember 20, 2025 Read More
Publications of the Week The New Frontier in Understanding Human and Mammalian Brain Development Nowakowski, T., et al. | November 13, 2025 Neurodevelopmental disorders that cause cognitive, behavioural or motor impairments affect around 15% of children and…karnottNovember 13, 2025 Read More
Publications of the Week Atomically Accurate De Novo Design of Antibodies With RFdiffusion Bennett, N., et al. | November 13, 2025 Despite the central role of antibodies in modern medicine, no method currently exists to design…karnottNovember 13, 2025 Read More
Publications of the Week Bottom-up Design of CA2+ Channels From Defined Selectivity Filter Geometry Liu, Y., et al. | November 5, 2025 Native ion channels play key roles in biological systems, and engineered versions are widely used…karnottNovember 5, 2025 Read More