Publications of the Week Metagenomic Estimation of Dietary Intake From Human StoolDiener, C., et al. | February 21, 2025Dietary intake is tightly coupled to gut microbiota composition, human metabolism and the incidence of…karnottFebruary 21, 2025 Read More
Publications of the Week Multiplex Generation and Single-Cell Analysis of Structural Variants in Mammalian GenomesPinglay, S., et al. | February 20, 2025The structural variants (SVs) present in mammalian genomes include deletions, insertions, inversions, duplications, translocations, extrachromosomal…karnottFebruary 20, 2025 Read More
Publications of the Week APMAT Analysis Reveals the Association Between CD8 T Cell Receptors, Cognate Antigen, and T Cell Phenotype and PersistenceXie, J., et al. | February 12, 2025Elucidating the relationships between a class I peptide antigen, a CD8 T cell receptor (TCR)…karnottFebruary 12, 2025 Read More
Publications of the Week Tissue-Resident Memory CD8 T Cell Diversity Is Spatiotemporally ImprintedReina-Campos, M., et al. | February 5, 2025This week, we profile a recent publication in Nature by Dr. Maximilian Heeg’s (pictured) lab…karnottFebruary 5, 2025 Read More
Publications of the Week A Novel Rapalog Shows Improved Safety vs. Efficacy in a Human Organoid Model of Polycystic Kidney DiseaseGulieva, R., et al. | February 3, 2025The mammalian target of rapamycin (mTOR) pathway is a therapeutic target in polycystic kidney disease…karnottFebruary 3, 2025 Read More
Publications of the Week De Novo Designed Proteins Neutralize Lethal Snake Venom ToxinsVázquez Torres, S., et al. | January 29, 2025This week, we profile a recent publication in Nature by Dr. Susana Vázquez Torres (pictured) …karnottJanuary 29, 2025 Read More
Publications of the Week Characterization of Clonal Dynamics Using Duplex Sequencing in Donor-Recipient Pairs Decades After Hematopoietic Cell TransplantationOshima, M., et al. | January 20, 2025Donor-associated clonal hematopoiesis (CH) has been reported in recipients of allogeneic hematopoietic cell transplantation (HCT);…karnottJanuary 20, 2025 Read More
Publications of the Week Brain-Wide Cell-Type-Specific Transcriptomic Signatures of Healthy Ageing in MiceJin, K., et al. | January 13, 2025Biological ageing can be defined as a gradual loss of homeostasis across various aspects of…karnottJanuary 13, 2025 Read More
Publications of the Week Cellular RNA Interacts with MAVS to Promote Antiviral SignalingGokhale, N., et al. | January 8, 2025RIG-I-like receptors (RLRs) are sensors that detect viral RNA in animal cells. RLRs signal to…karnottJanuary 8, 2025 Read More
Publications of the Week Adjusting for Principal Components Can Induce Collider Bias in Genome-Wide Association StudiesGrinde, K., et al. | January 6, 2025Principal component analysis (PCA) is widely used to control for population structure in genome-wide association…karnottJanuary 6, 2025 Read More