Publications of the Week Type I IFN Induces Long-Chain Acyl-CoA Synthetase 1 to Generate a Phosphatidic Acid Reservoir for Lipotoxic Saturated Fatty AcidsBarnhart, S., et al. | December 18, 2024Long-chain acyl-CoA synthetase 1 (ACSL1) catalyzes the conversion of long-chain fatty acids to acyl-CoAs. ACSL1…karnottDecember 18, 2024 Read More
Publications of the Week Identification and Annotation of Centromeric Hypomethylated Regions with Centromere Dip Region (CDR)-FinderLogsdon, G., et al. | December 17, 2024Centromeres are chromosomal regions historically understudied with sequencing technologies due to their repetitive nature and…karnottDecember 17, 2024 Read More
Publications of the Week Development and Validation of Predictive Models of Early Immune Effector Cell-Associated Hematotoxicity (eIPMs)Liang, E., et al. | December 10, 2024Immune effector cell-associated hematotoxicity (ICAHT) is associated with morbidity and mortality after chimeric antigen receptor…karnottDecember 10, 2024 Read More
Publications of the Week Calcium Dynamics of Skin-Resident Macrophages During Homeostasis and Tissue InjuryLeon, P., et al. | December 3, 2024Immune cells depend on rapid changes in intracellular calcium activity to modulate cell function. Skin…karnottDecember 3, 2024 Read More
Publications of the Week Broadly Inhibitory Antibodies to Severe Malaria Virulence ProteinsReyes, R., et al. | November 27, 2024Malaria pathology is driven by the accumulation of Plasmodium falciparum-infected erythrocytes in microvessels1. This process…karnottNovember 27, 2024 Read More
Publications of the Week Single-Cell Analysis of the Multiple Myeloma Microenvironment After Gamma-Secretase Inhibition and CAR T-Cell TherapyCoffey, D., et al. | November 25, 2024Chimeric antigen receptor (CAR) T-cells and bispecific antibodies (BsAb) targeting B-cell maturation antigen (BCMA) have…karnottNovember 25, 2024 Read More
Publications of the Week Attenuated Kidney Oxidative Metabolism in Young Adults with Type 1 DiabetesChoi, Y., et al. | November 20, 2024In type 1 diabetes (T1D), impaired insulin sensitivity may contribute to the development of diabetic…karnottNovember 20, 2024 Read More
Publications of the Week Targeting RSV-Neutralizing B Cell Receptors with Anti-Idiotypic AntibodiesScharffenberger, S., et al. | November 18, 2024Respiratory syncytial virus (RSV) causes lower respiratory tract infections with significant morbidity and mortality at…karnottNovember 18, 2024 Read More
Publications of the Week A Human Gut Faecalibacterium prausnitzii Fatty Acid Amide HydrolaseCheng, J., et al. | November 15, 2024The gut microbiota generate diverse bioactive compounds that can potentially affect host physiology. During bouts…karnottNovember 15, 2024 Read More
Publications of the Week Proteomic Analysis Uncovers Multi-Protein Signatures Associated with Early Diabetic Kidney Disease in Youth with Type 2 Diabetes MellitusPyle, L., et al. | November 14, 2024The onset of diabetic kidney disease (DKD) in youth with type 2 diabetes mellitus often…karnottNovember 14, 2024 Read More