Publications of the Week Attenuated Kidney Oxidative Metabolism in Young Adults with Type 1 DiabetesChoi, Y., et al. | November 20, 2024In type 1 diabetes (T1D), impaired insulin sensitivity may contribute to the development of diabetic…karnottNovember 20, 2024 Read More
Publications of the Week Targeting RSV-Neutralizing B Cell Receptors with Anti-Idiotypic AntibodiesScharffenberger, S., et al. | November 18, 2024Respiratory syncytial virus (RSV) causes lower respiratory tract infections with significant morbidity and mortality at…karnottNovember 18, 2024 Read More
Publications of the Week A Human Gut Faecalibacterium prausnitzii Fatty Acid Amide HydrolaseCheng, J., et al. | November 15, 2024The gut microbiota generate diverse bioactive compounds that can potentially affect host physiology. During bouts…karnottNovember 15, 2024 Read More
Publications of the Week Proteomic Analysis Uncovers Multi-Protein Signatures Associated with Early Diabetic Kidney Disease in Youth with Type 2 Diabetes MellitusPyle, L., et al. | November 14, 2024The onset of diabetic kidney disease (DKD) in youth with type 2 diabetes mellitus often…karnottNovember 14, 2024 Read More
Publications of the Week An IL-2 Mutein Increases Regulatory T Cell Suppression of Dendritic Cells via IL-10 and CTLA-4 to Promote T Cell AnergyJamison, B., et al. | November 7, 2024Interleukin-2 (IL-2) variants with increased CD25 dependence that selectively expand Foxp3+ regulatory T (TR) cells are…karnottNovember 7, 2024 Read More
Publications of the Week Label-Free, Real-Time Monitoring of Cytochrome C Drug Responses in Microdissected Tumor Biopsies with a Multi-Well Aptasensor PlatformNguyen, T., et al. | October 28, 2024Functional assays on intact tumor biopsies can complement genomics-based approaches for precision oncology, drug testing,…karnottOctober 28, 2024 Read More
Publications of the Week Integrated Multimodal Cell Atlas of Alzheimer’s DiseaseGabitto, M., et al. | October 22, 2024Alzheimer’s disease (AD) is the leading cause of dementia in older adults. Although AD progression…karnottOctober 22, 2024 Read More
Publications of the Week Viral Gene Drive Spread During Herpes Simplex Virus 1 Infection in MiceWalter, M., et al. | October 18, 2024Gene drives are genetic modifications designed to propagate efficiently through a population. Most applications rely…karnottOctober 18, 2024 Read More
Publications of the Week Host Cell Glycosylation Selects for Infection with CCR5- Versus CXCR4-Tropic HIV-1Itell, H., et al. | October 11, 2024Human immunodeficiency virus type 1 (HIV-1) infection involves a selection bottleneck that leads to transmission…karnottOctober 11, 2024 Read More
Publications of the Week Progression to Type 1 Diabetes in the DPT-1 and TN07 Clinical Trials Is Critically Associated with Specific Residues in HLA-DQA1-B1 HeterodimersZhao, L., et al. | October 4, 2024The aim of this work was to explore molecular amino acids (AAs) and related structures…karnottOctober 4, 2024 Read More