Publications of the Week

Identity-by-descent (IBD) mapping provides complementary signals to genome-wide association studies (GWASs) when multiple causal haplotypes…

The androgen receptor (AR) is a critical driver of prostate cancer (PCa). Here, to study…

Effective antitumor immunity ultimately depends on the priming and activation of tumor-specific cytotoxic CD8+ T…

Epistatic interactions present a major challenge in accurate genotype–phenotype correlation. Here, we combined high-throughput yeast…

RNA-driven protein aggregation leads to cellular dysregulation and contributes to the development of diseases and…

Lymph nodes (LNs) enable innate defense to limit pathogen dissemination while also driving adaptive immunity.…

Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD-TDP) exhibit predominantly cytoplasmic phosphorylated inclusions of…

The post-acute sequelae of SARS-CoV-2 (PASC), also known as long COVID, remain a significant health…

The multifaceted dysfunction of tumour-infiltrating T cells, including exhaustion and mitochondrial dysfunction, remains a major…

Somatic stem cell pools comprise diverse, highly specialized subsets whose individual contribution is critical for…