Publications of the Week Excess Cysteine Drives Conjugate Formation and Impairs Proliferation of NRF2-Activated Cancer Cells Brain, J., et al. | August 27, 2026 Cancer cells with constitutive NRF2 activation take up excess cystine beyond the cysteine demands of…karnottAugust 27, 2026 Read More
Publications of the Week needLR: Long-Read Structural Variant Annotation With Population-Scale Frequency Estimation Gustafson, J., et al. | August 25, 2026 We present needLR, a structural variant (SV) annotation tool that can be used for filtering…karnottAugust 25, 2026 Read More
Publications of the Week Approaching a Connectome of the Human Foveal Retina Kim, Y., et al. | August 18, 2026 Vision begins in the retina, an accessible outpost of the brain located at the back…karnottAugust 18, 2026 Read More
Publications of the Week SGLT2 Inhibition Modulates Metabolic, Vascular, and Inflammatory Molecular Markers in the Kidney in Youth With Type 1 Diabetes Bjornstad, P., et al. | August 10, 2026 Sodium-glucose cotransporter-2 (SGLT2) inhibitors can slow diabetic kidney disease, but less is known about their…karnottAugust 10, 2026 Read More
Publications of the Week The Genetic Architecture of Fibromyalgia Across 2.5 Million Individuals Kerrebijn, I., et al. | August 6, 2026 Fibromyalgia is a common and debilitating chronic pain syndrome of poorly understood etiology. Here we…karnottAugust 6, 2026 Read More
Publications of the Week Capturing the Dynamics of STAT6 Macrophage Polarization Using Bioluminescence Temporal Signatures Zheng, S., et al. | August 3, 2026 Signal transducer and activator of transcription 6 (STAT6) signaling is activated by interleukin 4 (IL-4)…karnottAugust 3, 2026 Read More
Publications of the Week Within-Patient Gene Transfer Between Transiently and Chronically Infecting Bacteria Causes Extreme Antibiotic Resistance During Lung Infections Karash, S., et al. | July 28, 2026 Antibiotic resistance arising during infections is generally thought to be due to mutations in pathogen…karnottJuly 28, 2026 Read More
Publications of the Week Germline CDK12 Variants in Aggressive Prostate Cancer Tolmeijer, S., et al. | July 22, 2026 CDK12 mutations occur in 2-7% of metastatic prostate cancers (mPCa) and are considered to be…karnottJuly 22, 2026 Read More
Publications of the Week CD28 Signaling Complexes Are Correlated with Patient Outcomes in Anti-CD19 41BB-Costimulation CAR T Cell Therapy Draper, I., et al. | July 15, 2026 Chimeric antigen receptor (CAR) T cells targeting CD19 achieve remarkable remissions in refractory B cell…karnottJuly 15, 2026 Read More
Publications of the Week Comparison of Specific Glucagon-Like Peptide-1 Receptor Agonists on Kidney Outcomes Among Patients with Type 2 Diabetes Neumiller, J., et al. | July 13, 2026 Glucagon-like peptide-1 (GLP-1) receptor agonist treatment is associated with lower risk for incident chronic kidney…karnottJuly 13, 2026 Read More