Publications of the Week Protein Overabundance Is Driven by Growth Robustness Choi, J., et al. | April 28, 2026 Protein expression levels optimize cell fitness: Too low an expression level of essential proteins will…karnottApril 28, 2026 Read More
Publications of the Week Distinct Tissue Niches Contribute to Prostate Tissue-Resident Memory CD8+ T Cell Differentiation and Heterogeneity Takehara, K., et al. | April 21, 2026 The prostate is an important exocrine organ, a barrier tissue of the male reproductive system,…karnottApril 21, 2026 Read More
Publications of the Week Spatial Multi-Omics Unveils the Monoclonal Origin, Neuroendocrine Plasticity, and Microenvironment Niches in Combined Small-Cell Lung Cancer Wang, Z., et al. | April 14, 2026 Combined small-cell lung cancer (cSCLC) is an aggressive subtype of SCLC with mixed histologic components.…karnottApril 14, 2026 Read More
Publications of the Week Functional Dissection of Noncoding Variants Associated with Rheumatoid Arthritis Jajodia, A., et al. | April 8, 2026 Noncoding variants are critical to our understanding of the genetic basis of diseases and disorders…karnottApril 8, 2026 Read More
Publications of the Week A Common 19 BP APOE Enhancer Deletion Is Protective Against Alzheimer’s Disease in African Americans Brutman, J., et al. | March 30, 2026 The APOE-ε4/ε4 genotype is the strongest genetic risk factor for sporadic Alzheimer’s disease, though the…karnottMarch 30, 2026 Read More
Publications of the Week Divergent Effects of a Treg-Selective IL-2 Mutein on Influenza-Specific T Cell Responses Albe, J., et al. | March 25, 2026 Enhancing regulatory T cell (Treg) function offers a compelling therapeutic strategy for autoimmune disease. Engineered…karnottMarch 25, 2026 Read More
Publications of the Week Dynamics of Phage-Host Interactions in Bacteroides fragilis Resolved by Single-Cell Transcriptomics Gupta, A., et al. | March 23, 2026 The interactions between lytic phages and their hosts are typically studied in bulk culture, which…karnottMarch 23, 2026 Read More
Publications of the Week Subcellular Nanoparticle Trafficking Investigated With Label-Free, Live Cell Imaging Nelson, E., et al. | March 9, 2026 Nanoparticle drug delivery systems have significant potential to transform precision medicine due to their ability…karnottMarch 9, 2026 Read More
Publications of the Week Multiple-Testing Corrections in Case-Control Studies Using Identity-By-Descent Segments Temple, S., et al. | March 6, 2026 Identity-by-descent (IBD) mapping provides complementary signals to genome-wide association studies (GWASs) when multiple causal haplotypes…karnottMarch 6, 2026 Read More
Publications of the Week Genome-Scale CRISPR Screens Identify PTGES3 as a Direct Modulator of Androgen Receptor Function in Advanced Prostate Cancer Li, H., et al. | February 25, 2026 The androgen receptor (AR) is a critical driver of prostate cancer (PCa). Here, to study…karnottFebruary 25, 2026 Read More