Publications of the Week Divergent Effects of a Treg-Selective IL-2 Mutein on Influenza-Specific T Cell Responses Albe, J., et al. | March 25, 2026 Enhancing regulatory T cell (Treg) function offers a compelling therapeutic strategy for autoimmune disease. Engineered…karnottMarch 25, 2026 Read More
Publications of the Week Dynamics of Phage-Host Interactions in Bacteroides fragilis Resolved by Single-Cell Transcriptomics Gupta, A., et al. | March 23, 2026 The interactions between lytic phages and their hosts are typically studied in bulk culture, which…karnottMarch 23, 2026 Read More
Publications of the Week Subcellular Nanoparticle Trafficking Investigated With Label-Free, Live Cell Imaging Nelson, E., et al. | March 9, 2026 Nanoparticle drug delivery systems have significant potential to transform precision medicine due to their ability…karnottMarch 9, 2026 Read More
Publications of the Week Multiple-Testing Corrections in Case-Control Studies Using Identity-By-Descent Segments Temple, S., et al. | March 6, 2026 Identity-by-descent (IBD) mapping provides complementary signals to genome-wide association studies (GWASs) when multiple causal haplotypes…karnottMarch 6, 2026 Read More
Publications of the Week Genome-Scale CRISPR Screens Identify PTGES3 as a Direct Modulator of Androgen Receptor Function in Advanced Prostate Cancer Li, H., et al. | February 25, 2026 The androgen receptor (AR) is a critical driver of prostate cancer (PCa). Here, to study…karnottFebruary 25, 2026 Read More
Publications of the Week Intratumoral Three-Cell-Type Clusters Are a Conserved Feature of Endogenous Antitumor Immunity Damle, S., et al. | February 17, 2026 Effective antitumor immunity ultimately depends on the priming and activation of tumor-specific cytotoxic CD8+ T…karnottFebruary 17, 2026 Read More
Publications of the Week Predicting Epistasis Across Proteins by Structural Logic Tang, M., et al. | February 11, 2026 Epistatic interactions present a major challenge in accurate genotype–phenotype correlation. Here, we combined high-throughput yeast…karnottFebruary 11, 2026 Read More
Publications of the Week DUX4-Induced Hsatii Rna Accumulation Drives Protein Aggregation, Impacting RNA Processing Pathways Arends, T., et al. | February 2, 2026 RNA-driven protein aggregation leads to cellular dysregulation and contributes to the development of diseases and…karnottFebruary 2, 2026 Read More
Publications of the Week Dendritic Cells Regulate the Innate-Adaptive Balance in Lymph Nodes for Optimal Host Defense Huang, J., et al. | January 30, 2026 Lymph nodes (LNs) enable innate defense to limit pathogen dissemination while also driving adaptive immunity.…karnottJanuary 30, 2026 Read More
Publications of the Week Calcineurin Depletion Coincides with Phosphorylated TDP-43 Deposition in a Mouse Model of ALS/FTLD-TDP Waldherr, S., et al. | January 27, 2026 Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD-TDP) exhibit predominantly cytoplasmic phosphorylated inclusions of…karnottJanuary 27, 2026 Read More