Publications of the Week Decoding Post-Transcriptional Regulatory Networks by RNA-Linked CRISPR Screening in Human CellsNugent, P., et al. | June 4, 2025RNAs undergo a complex choreography of metabolic processes that are regulated by thousands of RNA-associated…karnottJune 4, 2025 Read More
Publications of the Week Myeloid Cell Genome-Wide Screen Identifies Variants Associated with Mycobacterium Tuberculosis-Induced Cytokine Transcriptional ResponsesIvie, J.J., et al. | May 28, 2025Immune and clinical outcomes to Mycobacterium tuberculosis (Mtb) infection vary greatly between individuals yet the…sciencecityMay 28, 2025 Read More
Publications of the Week Anti-HSP90α IgG May Protect Against Antiphospholipid Syndrome in Systemic Lupus Erythematosus by Reducing Platelet ActivationBarguil Macêdo, M., et al. | May 26, 2025Natural autoantibodies (NAAbs) are immunoglobulins generated in the absence of antigen provocation, with no inherent…sciencecityMay 26, 2025 Read More
Publications of the Week KAT5 Regulates Neurodevelopmental States Associated with G0-like Populations in GlioblastomaMihalas, A.B., et al. | May 21, 2025Quiescence cancer stem-like cells may play key roles in promoting tumor cell heterogeneity and recurrence…sciencecityMay 21, 2025 Read More
Publications of the Week Drosophila Epidermal Cells Are Intrinsically Mechanosensitive and Modulate Nociceptive Behavioral OutputsYoshino, J., et al. | May 20, 2025Somatosensory neurons (SSNs) that detect and transduce mechanical, thermal, and chemical stimuli densely innervate an…sciencecityMay 20, 2025 Read More
Publications of the Week In Vivo Functional Screens Reveal KEAP1 Loss as a Driver of Chemoresistance in Small Cell Lung CancerBrumage, L., et al. | May 15, 2025Exquisitely chemosensitive initially, small cell lung cancer (SCLC) exhibits dismal outcomes owing to rapid transition…karnottMay 15, 2025 Read More
Publications of the Week Enteric Tuft Cell Inflammasome Activation Drives NKp46+ILC3 IL22 via PGD2 and Inhibits SalmonellaChurchill, M., et al. | May 14, 2025To distinguish pathogens from commensals, the intestinal epithelium employs cytosolic innate immune sensors. Activation of…karnottMay 14, 2025 Read More
Publications of the Week Functional and Antigenic Landscape of the Nipah Virus Receptor-Binding ProteinLarsen, B., et al. | May 7, 2025Nipah virus recurrently spills over to humans, causing fatal infections. The viral receptor-binding protein (RBP…karnottMay 7, 2025 Read More
Publications of the Week In Vivo Functional Screens Reveal KEAP1 Loss as a Driver of Chemoresistance in Small Cell Lung CancerBrumage, L., et al. | May 1, 2025Exquisitely chemosensitive initially, small cell lung cancer (SCLC) exhibits dismal outcomes owing to rapid transition…karnottMay 1, 2025 Read More
Publications of the Week Human De Novo Mutation Rates From a Four-Generation Pedigree ReferencePorubsky, D., et al. | April 29, 2025Understanding the human de novo mutation (DNM) rate requires complete sequence information1. Here using five…karnottApril 29, 2025 Read More