Publications of the Week Type I IFN Induces Long-Chain Acyl-CoA Synthetase 1 to Generate a Phosphatidic Acid Reservoir for Lipotoxic Saturated Fatty Acids Barnhart, S., et al. | December 18, 2024 Long-chain acyl-CoA synthetase 1 (ACSL1) catalyzes the conversion of long-chain fatty acids to acyl-CoAs. ACSL1…karnottDecember 18, 2024 Read More
Publications of the Week Identification and Annotation of Centromeric Hypomethylated Regions with Centromere Dip Region (CDR)-Finder Logsdon, G., et al. | December 17, 2024 Centromeres are chromosomal regions historically understudied with sequencing technologies due to their repetitive nature and…karnottDecember 17, 2024 Read More
Publications of the Week Development and Validation of Predictive Models of Early Immune Effector Cell-Associated Hematotoxicity (eIPMs) Liang, E., et al. | December 10, 2024 Immune effector cell-associated hematotoxicity (ICAHT) is associated with morbidity and mortality after chimeric antigen receptor…karnottDecember 10, 2024 Read More
Publications of the Week Calcium Dynamics of Skin-Resident Macrophages During Homeostasis and Tissue Injury Leon, P., et al. | December 3, 2024 Immune cells depend on rapid changes in intracellular calcium activity to modulate cell function. Skin…karnottDecember 3, 2024 Read More
Publications of the Week Broadly Inhibitory Antibodies to Severe Malaria Virulence Proteins Reyes, R., et al. | November 27, 2024 Malaria pathology is driven by the accumulation of Plasmodium falciparum-infected erythrocytes in microvessels1. This process…karnottNovember 27, 2024 Read More
Publications of the Week Single-Cell Analysis of the Multiple Myeloma Microenvironment After Gamma-Secretase Inhibition and CAR T-Cell Therapy Coffey, D., et al. | November 25, 2024 Chimeric antigen receptor (CAR) T-cells and bispecific antibodies (BsAb) targeting B-cell maturation antigen (BCMA) have…karnottNovember 25, 2024 Read More
Publications of the Week Attenuated Kidney Oxidative Metabolism in Young Adults with Type 1 Diabetes Choi, Y., et al. | November 20, 2024 In type 1 diabetes (T1D), impaired insulin sensitivity may contribute to the development of diabetic…karnottNovember 20, 2024 Read More
Publications of the Week Targeting RSV-Neutralizing B Cell Receptors with Anti-Idiotypic Antibodies Scharffenberger, S., et al. | November 18, 2024 Respiratory syncytial virus (RSV) causes lower respiratory tract infections with significant morbidity and mortality at…karnottNovember 18, 2024 Read More
Publications of the Week A Human Gut Faecalibacterium prausnitzii Fatty Acid Amide Hydrolase Cheng, J., et al. | November 15, 2024 The gut microbiota generate diverse bioactive compounds that can potentially affect host physiology. During bouts…karnottNovember 15, 2024 Read More
Publications of the Week Proteomic Analysis Uncovers Multi-Protein Signatures Associated with Early Diabetic Kidney Disease in Youth with Type 2 Diabetes Mellitus Pyle, L., et al. | November 14, 2024 The onset of diabetic kidney disease (DKD) in youth with type 2 diabetes mellitus often…karnottNovember 14, 2024 Read More