Publications of the Week

Antibody inhibitors pose an ongoing challenge to the treatment of subjects with inherited protein deficiency…

Protein–protein interactions (PPIs) regulate many cellular processes and engineered PPIs have cell and gene therapy…

RIT1 is a rare and understudied oncogene in lung cancer. Despite structural similarity to other…

Mycobacterium tuberculosis (Mtb) exposure leads to a range of outcomes including clearance, latent TB infection…

Ligands such as insulin, epidermal growth factor, platelet-derived growth factor, and nerve growth factor (NGF)…

Current CD33-targeted immunotherapies typically recognize the membrane-distal V-set domain of CD33. Here, we show decreasing…

Here, we report detailed clinicopathologic evaluation of 2 individuals with pathogenic variants in TBK1, including one…

Quantifying labeled cells in fluorescent microscopy is a fundamental aspect of modern biology. Critically, the…

Neuronal anatomy is central to the organization and function of brain cell types. However, anatomical…

The conserved SKN-1A/Nrf1 transcription factor regulates the expression of proteasome subunit genes and is essential…