Publications of the Week Multipotent Progenitors and Hematopoietic Stem Cells Arise Independently from Hemogenic Endothelium in the Mouse EmbryoDignum, T., et al. | September 29, 2021During embryogenesis, waves of hematopoietic progenitors develop from hemogenic endothelium (HE) prior to the emergence…dcorriganSeptember 29, 2021 Read More
Publications of the Week Pharmacologic Therapy for Engraftment Arrhythmia Induced by Transplantation of Human CardiomyocytesNakamura, K., et al. | September 24, 2021Heart failure remains a significant cause of morbidity and mortality following myocardial infarction. Cardiac remuscularization…dcorriganSeptember 24, 2021 Read More
Publications of the Week Signature Morpho-Electric, Transcriptomic, and Dendritic Properties of Human Layer 5 Neocortical Pyramidal NeuronsKalmbach, B., et al. | September 24, 2021In the neocortex, subcerebral axonal projections originate largely from layer 5 (L5) extratelencephalic-projecting (ET) neurons.…dcorriganSeptember 24, 2021 Read More
Publications of the Week A Modified Fluctuation Assay Reveals a Natural Mutator Phenotype That Drives Mutation Spectrum Variation within Saccharomyces cerevisiaeJiang, P., et al. | September 21, 2021The authors used a combination of computational and experimental techniques to study the variation of…dcorriganSeptember 21, 2021 Read More
Publications of the Week Baseline Gut Metagenomic Functional Gene Signature Associated with Variable Weight Loss Responses following a Healthy Lifestyle Intervention in HumansDiener, C., et al. | September 17, 2021Some people have a harder time losing weight than others. The current study, along with…dcorriganSeptember 17, 2021 Read More
Publications of the Week Integrating T Cell Receptor Sequences and Transcriptional Profiles by Clonotype Neighbor Graph Analysis (CoNGA)Schattgen, S. A., et al. | September 16, 2021Links between T cell clonotypes, as defined by T cell receptor (TCR) sequences, and phenotype,…dcorriganSeptember 16, 2021 Read More
Publications of the Week Integrated Analysis of Plasma and Single Immune Cells Uncovers Metabolic Changes in Individuals with COVID-19Lee., J.W., et al. | September 14, 2021A better understanding of the metabolic alterations in immune cells during severe acute respiratory syndrome…dcorriganSeptember 14, 2021 Read More
Publications of the Week Discovery of Synthetic Lethal and Tumor Suppressor Paralog Pairs in the Human GenomeParrish, P. C. R., et al. | September 10, 2021For the past decade, scientists have performed genome-wide screens to identify important cancer genes –…dcorriganSeptember 10, 2021 Read More
Publications of the Week Antibodies to EGF Receptor Family Members Can Upregulate Tumor ImmunityMin, D., et al. | September 6, 2021Immunologic mechanisms influence how a cancer patient responds to therapy. Monoclonal antibodies (mAbs) to the…dcorriganSeptember 6, 2021 Read More
Publications of the Week Therapeutic Targeting of Mesothelin with Chimeric Antigen Receptor T Cells in Acute Myeloid LeukemiaLe, Q., et al. | September 3, 2021A significant barrier to effective immunotherapy in AML is the shared immunophenotype between AML and…dcorriganSeptember 3, 2021 Read More