Publications of the Week Nuclear Pore Complexes Mediate Subtelomeric Gene Silencing by Regulating PCNA Levels on Chromatin Aitchison, J. D., et al. | June 30, 2023 The nuclear pore complex (NPC) physically interacts with chromatin and regulates gene expression. The Saccharomyces cerevisiae…pthomsonJune 30, 2023 Read More
Publications of the Week A Model of the Post-implantation Human Embryo Derived from Pluripotent Stem Cells Zernicka-Goetz, M., et al. | June 30, 2023 Stem cell-derived models of the embryo are important tools to interrogate developmental events and tissue-tissue…pthomsonJune 30, 2023 Read More
Publications of the Week Role of Mitochondria in the Myopathy of Juvenile Dermatomyositis and Implications for Skeletal Muscle Calcinosis Lood, C., et al. | June 27, 2023 Patients with JDM exhibited elevated levels of mitochondrial markers associated with muscle damage and calcinosis.…pthomsonJune 27, 2023 Read More
Publications of the Week Minimizing the Off-Target Frequency of the CRISPR/Cas9 System via Zwitterionic Polymer Conjugation and Peptide Fusion† Han, Y. et al. | June 22, 2023 The clustered, regularly interspaced, short palindromic repeats (CRISPR)–associated protein 9 (Cas9) system is a powerful…pthomsonJune 22, 2023 Read More
Publications of the Week The Unfolded Protein Response Components IRE1α and XBP1 Promote Human Coronavirus Infection Fink, S. L., et al. | June 13, 2023 The cellular processes that support human coronavirus replication and contribute to the pathogenesis of severe…pthomsonJune 13, 2023 Read More
Publications of the Week Metrologically Traceable Quantification of 3 Apolipoprotein E Isoforms in Cerebrospinal Fluid Hoofnagle, A. N., et al. | June 13, 2023 APOE genotype is associated with Alzheimer's disease. Thus, the concentration of apolipoprotein E (apoE) isoforms…pthomsonJune 13, 2023 Read More
Publications of the Week Analysis of Antibiotic Exposure and Development of Acute Graft-vs-Host Disease Following Allogeneic Hematopoietic Cell Transplantation Rashidi, A., et al. | June 12, 2023 Certain antibiotic exposures have been associated with increased rates of acute graft-vs-host disease (aGVHD) after…pthomsonJune 12, 2023 Read More
Publications of the Week Mitochondrial N-Formyl Methionine Peptides Contribute to Exaggerated Neutrophil Activation in Patients With COVID-19 Kuley, R., et al. | June 7, 2023 Neutrophil dysregulation is well established in COVID-19. However, factors contributing to neutrophil activation in COVID-19…sciencecityJune 7, 2023 Read More
Publications of the Week Identification of Broad, Potent Antibodies to Functionally Constrained Regions of SARS-CoV-2 Spike Following a Breakthrough Infection Guenthoer, J., et al. | June 6, 2023 The antiviral benefit of antibodies can be compromised by viral escape especially for rapidly evolving…sciencecityJune 6, 2023 Read More
Publications of the Week Several Cell-Intrinsic Effectors Drive Type I Interferon-Mediated Restriction of HIV-1 in Primary CD4+ T Cells Itell, H.L., et al. | May 30, 2023 Type I interferon (IFN) upregulates proteins that inhibit HIV within infected cells. Prior studies have…sciencecityMay 30, 2023 Read More