Publications of the Week

Nature only samples a small fraction of the sequence space that can fold into stable…

Alzheimer's disease (AD) is a common neurodegenerative disorder and a mechanistically complex disease. For the…

Stability of eukaryotic mRNAs is associated with their codon, amino acid, and GC content. Yet,…

The tumour-associated microbiota is an intrinsic component of the tumour microenvironment across human cancer types1,2.…

Methods for acquiring spatially resolved omics data from complex tissues use barcoded DNA arrays of…

Cancer-associated fibroblasts (CAFs) mediate an immunosuppressive effect, but the underlying mechanism remains incompletely defined. Here…

Chromatin profiling at locus resolution uncovers gene regulatory features that define cell types and developmental…

A fundamental step in regeneration is rapid growth to replace lost tissue. Cells must generate…

Kawasaki disease is a systemic vasculitis, especially of the coronary arteries, affecting children. Despite extensive…

Therapeutics that inhibit IL-6 at different points in its signaling pathway are in clinical use…