Publications of the Week A TfR-Binding Cystine-Dense Peptide Promotes Blood–Brain Barrier Penetration of Bioactive Molecules Olson, J.M., et al. | April 30, 2020 Transferrin receptor (TfR) binding entities can be used as vehicles for CNS drug delivery, however…eabramovichApril 30, 2020 Read More
Publications of the Week Coevolution of Host-Plasmid Pairs Facilitates the Emergence of Novel Multidrug Resistance Kerr, B., et al. | April 24, 2020 Multidrug resistance (MDR) of pathogens is an ongoing public health crisis exacerbated by the horizontal…emcguinnApril 24, 2020 Read More
Publications of the Week RhlR-Regulated Acyl-Homoserine Lactone Quorum Sensing in a Cystic Fibrosis Isolate of Pseudomonas aeruginosa Dandekar, A.A., et al. | April 22, 2020 The opportunistic pathogen Pseudomonas aeruginosa is a leading cause of airway infection in cystic fibrosis…emcguinnApril 22, 2020 Read More
Publications of the Week Intermediate Progenitors Support Migration of Neural Stem Cells into Dentate Gyrus Outer Neurogenic Niches Nelson, B.R., et al. | April 16, 2020 The hippocampal dentate gyrus (DG) is a unique brain region maintaining neural stem cells (NCSs)…emcguinnApril 16, 2020 Read More
Publications of the Week Effective CRISPRa-Mediated Control of Gene Expression in Bacteria Must Overcome Strict Target Site Requirements Fontana, J., et al. | April 14, 2020 The authors describe several features of bacterial genes that impose stringent requirements on CRISPR-Cas tools…eabramovichApril 14, 2020 Read More
Publications of the Week Resolving the Synaptic versus Developmental Dichotomy of Autism Risk Genes Heavner, W.H., & Smith, S.E.P. | April 10, 2020 Autism Spectrum Disorder (ASD) risk genes are often described as either developmental or synaptic. However,…sciencecityApril 10, 2020 Read More
Publications of the Week Phenomics-Based Quantification of CRISPR-Induced Mosaicism in Zebrafish Watson, C.J., et al. | April 8, 2020 This manuscript provides validation of an approach to rapidly screen zebrafish using first-generation CRISPR-edited mutants…sciencecityApril 8, 2020 Read More
Publications of the Week Dimensionality Reduction by UMAP to Visualize Physical and Genetic Interactions Dorrity, M.W., et al. | April 3, 2020 Dimensionality reduction is often used to visualize complex expression profiling data. Here, we use the…sciencecityApril 3, 2020 Read More
Publications of the Week RecV Recombinase System for In Vivo Targeted Optogenomic Modifications of Single Cells or Cell Populations Yao, S., et al. | April 1, 2020 Brain circuits comprise vast numbers of interconnected neurons with diverse molecular, anatomical and physiological properties.…sciencecityApril 1, 2020 Read More
Publications of the Week Remnants of the Triglyceride-Rich Lipoproteins, Diabetes, and Cardiovascular Disease Chait, A., et al. | March 26, 2020 Diabetes is now a pandemic disease. Moreover, a large number of people with prediabetes are…sciencecityMarch 26, 2020 Read More