Publications of the Week Candidate Silencer Elements for the Human and Mouse Genomes Jayavelu, N.D., et al. | March 12, 2020 The study of gene regulation is dominated by a focus on the control of gene…sciencecityMarch 12, 2020 Read More
Publications of the Week Spatial Modeling of Prostate Cancer Metabolic Gene Expression Reveals Extensive Heterogeneity and Selective Vulnerabilities Wang, Y., et al. | March 10, 2020 Targeting metabolic aberrations has been a major focus in cancer research, and genome-scale metabolic network…sciencecityMarch 10, 2020 Read More
Publications of the Week The CD33 Splice Isoform Lacking Exon 2 as Therapeutic Target in Human Acute Myeloid Leukemia Godwin, C.D., et al. | March 6, 2020 Data from several randomized studies have shown that a CD33 antibody-drug conjugate reduces relapse risks…sciencecityMarch 6, 2020 Read More
Publications of the Week Increased Islet Antigen–Specific Regulatory and Effector CD4+ T Cells in Healthy Individuals with the Type 1 Diabetes–Protective Haplotype Wen, X., et al. | March 3, 2020 Polymorphic histocompatibility genes in the HLA locus have a strong influence on genetic susceptibility to…sciencecityMarch 3, 2020 Read More
Publications of the Week STAT Signaling Modifies Ascl1 Chromatin Binding and Limits Neural Regeneration from Muller Glia in Adult Mouse Retina Jorstad, N.L., et al. | February 27, 2020 Müller glia (MG) serve as sources for retinal regeneration in non-mammalian vertebrates. We find that…sciencecityFebruary 27, 2020 Read More
Publications of the Week Embryonic Barcoding of Equipotent Mammary Progenitors Functionally Identifies Breast Cancer Drivers Ying, Z., & Beronja, S., | February 24, 2020 Identification of clinically relevant drivers of breast cancers in intact mammary epithelium is critical for…sciencecityFebruary 24, 2020 Read More
Publications of the Week Connect-Seq to Superimpose Molecular on Anatomical Neural Circuit Maps Hanchate, N.K., et al. | February 21, 2020 Single-cell transcriptomics has emerged as a powerful means to define the molecular heterogeneity of brain…sciencecityFebruary 21, 2020 Read More
Publications of the Week Mechanisms of Endogenous HIV-1 Reactivation by Endocervical Epithelial Cells Gornalusse, G.G., et al. | February 20, 2020 The authors have demonstrated that the immunological activities of certain epithelial cells, in this case…sciencecityFebruary 20, 2020 Read More
Publications of the Week Broadly Neutralizing Antibodies for HIV Prevention Karuna, S.T., & Corey, L. | February 13, 2020 In the last decade, over a dozen potent broadly neutralizing antibodies (bnAbs) to several HIV…sciencecityFebruary 13, 2020 Read More
Publications of the Week Single-Cell Transcriptomic Comparison of Human Fetal Retina, hPSC-Derived Retinal Organoids, and Long-Term Retinal Cultures Sridhar, A., et al. | February 10, 2020 The authors used single cell transcriptomic techniques to compare retinal organoids to normal fetal development.…sciencecityFebruary 10, 2020 Read More