Publications of the Week Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor TargetingSrivastava, S., et al. | April 5, 2019Many potential targets for CAR-T cells in solid tumors are expressed in some normal tissues,…sciencecityApril 5, 2019 Read More
Publications of the Week Old Cogs, New Tricks: The Evolution of Gene Expression in a Chromatin ContextTalbert, P.B., et al. | April 4, 2019Sophisticated gene-regulatory mechanisms probably evolved in prokaryotes billions of years before the emergence of modern…sciencecityApril 4, 2019 Read More
Publications of the Week Vitamin D-Binding Protein Deficiency and Homozygous Deletion of the GC GeneHenderson, C.M., et al. | April 2, 2019A 58-year-old woman with debilitating ankylosing spondylitis who was born to consanguineous parents was found…sciencecityApril 2, 2019 Read More
Publications of the Week Mechanisms of Small Heat Shock ProteinsJanowska, M.K., et al. | March 27, 2019Small heat shock proteins (sHSPs) are ATP-independent chaperones that delay formation of harmful protein aggregates.…sciencecityMarch 27, 2019 Read More
Publications of the Week Contractile Forces in Platelet Aggregates under Microfluidic Shear Gradients Reflect Platelet Inhibition and Bleeding RiskTing, L.H., et al. | March 25, 2019My lab focuses on the biomechanical behavior of human cells in the cardiovascular system, i.e.…sciencecityMarch 25, 2019 Read More
Publications of the Week Alterations in Phosphorylation of Hepatocyte Ribosomal Protein S6 Control Plasmodium Liver Stage InfectionGlennon, E.K.K., et al. | March 22, 2019The Kaushansky Lab in the Center for Global Infectious Disease Research at Seattle Children’s Research…sciencecityMarch 22, 2019 Read More
Publications of the Week Distinct Progenitor Populations Mediate Regeneration in the Zebrafish Lateral LineThomas, E.D. and Raible, D.W. | March 20, 2019Mechanosensory hair cells of the zebrafish lateral line regenerate rapidly following damage. These renewed hair…sciencecityMarch 20, 2019 Read More
Publications of the Week Genomic and Molecular Characterization of Preterm BirthKnijnenburg, T.A., et al. | March 19, 2019Preterm birth (PTB) complications are the leading cause of long-term morbidity and mortality in children.…sciencecityMarch 19, 2019 Read More
Publications of the Week Uncovering and Resolving Challenges of Quantitative Modeling in a Simplified Community of Interacting CellsHart, S.F.M., et al. | March 15, 2019Quantitative modeling is useful for predicting behaviors of a system and for rationally constructing or…sciencecityMarch 15, 2019 Read More
Publications of the Week The Hypothalamic Arcuate Nucleus-Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1Brown, J.M., et al. | March 13, 2019In rodent models of type 2 diabetes (T2D), sustained remission of diabetic hyperglycemia can be…sciencecityMarch 13, 2019 Read More