Publications of the Week Human 5′ UTR Design and Variant Effect Prediction from a Massively Parallel Translation AssaySample, P.J., et al. | July 19, 2019There are two main applications for this work. First, the scientists can use their models…sciencecityJuly 19, 2019 Read More
Publications of the Week Genetic Variation, Comparative Genomics, and the Diagnosis of DiseaseEvan Eichler | July 17, 2019The genome is not akin to a string of fixed length. Many large segments of…sciencecityJuly 17, 2019 Read More
Publications of the Week Pandemic Fluoroquinolone Resistant Escherichia coli Clone ST1193 Emerged via Simultaneous Homologous Recombinations in 11 Gene LociTchesnokova, V., et al. | July 15, 2019This research shows that pandemic multi-drug resistant (‘superbug’) strains can emerge virtually instantly, without a…sciencecityJuly 15, 2019 Read More
Publications of the Week Fasting Prevents Hypoxia-Induced Defects of Proteostasis in C. ElegansIranon, N.N., et al. | July 10, 2019Low oxygen conditions (hypoxia) can impair essential physiological processes and cause cellular damage and death.…sciencecityJuly 10, 2019 Read More
Publications of the Week Interferon-λ Modulates Dendritic Cells to Facilitate T Cell Immunity during Infection with Influenza a VirusHemann, E.A., et al. | July 8, 2019Type III interferon (IFN-λ) is important for innate immune protection at mucosal surfaces and has…sciencecityJuly 8, 2019 Read More
Publications of the Week T Cell Receptor Gene Therapy Targeting WT1 Prevents Acute Myeloid Leukemia Relapse Post-TransplantChapuis, A.G., et al. | July 5, 2019Relapse after allogeneic hematopoietic cell transplantation (HCT) is the leading cause of death in patients…sciencecityJuly 5, 2019 Read More
Publications of the Week Classification of Electrophysiological and Morphological Neuron Types in the Mouse Visual CortexGouwens, N.W., et al. | July 1, 2019Understanding the diversity of cell types in the brain has been an enduring challenge and…sciencecityJuly 1, 2019 Read More
Publications of the Week Intratumoral Activation of the Necroptotic Pathway Components RIPK1 and RIPK3 Potentiates Antitumor ImmunitySnyder, A.G., et al. | June 28, 2019Although the signaling events that induce different forms of programmed cell death are well defined,…sciencecityJune 28, 2019 Read More
Publications of the Week Complete Single Neuron Reconstruction Reveals Morphological Diversity in Molecularly Defined Claustral and Cortical Neuron TypesWang, Y., et al. | June 25, 2019Ever since the seminal findings of Ramon y Cajal, dendritic and axonal morphology has been…sciencecityJune 25, 2019 Read More
Publications of the Week Disentangling Strictly Self-Serving Mutations from Win-Win Mutations in a Mutualistic Microbial CommunityHart, S.F.M., et al. | June 21, 2019Mutualisms can be promoted by pleiotropic win-win mutations which directly benefit self (self-serving) and partner…sciencecityJune 21, 2019 Read More