Publications of the Week Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-Helminth Immunity in the Small Intestine But Are Dispensable for Anti-Protist Immunity McGinty, J.W., et al. | March 23, 2020 How do tuft cells regulate type 2 immune responses? Initial work identified the cytokine IL-25…sciencecityMarch 23, 2020 Read More
Publications of the Week Tissue-Resident T Cell Derived Cytokines Eliminate Herpes Simplex Virus-2 Infected Cells Roychoudhury, P., et al. | March 19, 2020 The authors have developed a realistic 3D model which captures the mechanisms that allow a…sciencecityMarch 19, 2020 Read More
Publications of the Week The Functional Activity of E-Cadherin Controls Tumor Cell Metastasis at Multiple Steps Na, TY., et al. | March 18, 2020 The expression of E-cadherin has been implicated in tumor metastasis, often as a tumor suppressor,…sciencecityMarch 18, 2020 Read More
Publications of the Week Engineering Heart Morphogenesis Mandrycky, C.J., et al. | March 16, 2020 There is high potential for current technologies to be used to recapitulate heart development in vitro…sciencecityMarch 16, 2020 Read More
Publications of the Week Candidate Silencer Elements for the Human and Mouse Genomes Jayavelu, N.D., et al. | March 12, 2020 The study of gene regulation is dominated by a focus on the control of gene…sciencecityMarch 12, 2020 Read More
Publications of the Week Spatial Modeling of Prostate Cancer Metabolic Gene Expression Reveals Extensive Heterogeneity and Selective Vulnerabilities Wang, Y., et al. | March 10, 2020 Targeting metabolic aberrations has been a major focus in cancer research, and genome-scale metabolic network…sciencecityMarch 10, 2020 Read More
Publications of the Week The CD33 Splice Isoform Lacking Exon 2 as Therapeutic Target in Human Acute Myeloid Leukemia Godwin, C.D., et al. | March 6, 2020 Data from several randomized studies have shown that a CD33 antibody-drug conjugate reduces relapse risks…sciencecityMarch 6, 2020 Read More
Publications of the Week Increased Islet Antigen–Specific Regulatory and Effector CD4+ T Cells in Healthy Individuals with the Type 1 Diabetes–Protective Haplotype Wen, X., et al. | March 3, 2020 Polymorphic histocompatibility genes in the HLA locus have a strong influence on genetic susceptibility to…sciencecityMarch 3, 2020 Read More
Publications of the Week STAT Signaling Modifies Ascl1 Chromatin Binding and Limits Neural Regeneration from Muller Glia in Adult Mouse Retina Jorstad, N.L., et al. | February 27, 2020 Müller glia (MG) serve as sources for retinal regeneration in non-mammalian vertebrates. We find that…sciencecityFebruary 27, 2020 Read More
Publications of the Week Embryonic Barcoding of Equipotent Mammary Progenitors Functionally Identifies Breast Cancer Drivers Ying, Z., & Beronja, S., | February 24, 2020 Identification of clinically relevant drivers of breast cancers in intact mammary epithelium is critical for…sciencecityFebruary 24, 2020 Read More