Publications of the Week Deep Mutational Scanning of Hemagglutinin Helps Predict Evolutionary Fates of Human H3N2 Influenza VariantsLee, J.M., et al. | August 24, 2018Human influenza virus rapidly accumulates mutations in its major surface protein hemagglutinin (HA). The evolutionary…sciencecityAugust 24, 2018 Read More
Publications of the Week Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic ModuleHsu, P.L., et al. | August 22, 2018The SET1/MLL family of histone methyltransferases is conserved in eukaryotes and regulates transcription by catalyzing…sciencecityAugust 22, 2018 Read More
Publications of the Week Single-Molecule Analysis of a Viral Fusion Protein Illuminates a Fusion-Active Intermediate StateBenhaim, M. and Lee, K.K. | August 20, 2018The influenza virus hemagglutinin (HA) fusion glycoprotein mediates viral entry into host cells through its…sciencecityAugust 20, 2018 Read More
Publications of the Week B Cell Adaptor for PI3-Kinase (BCAP) Modulates CD8+ Effector and Memory T Cell DifferentiationSingh, M.D., et al. | August 17, 2018CD8+ T cells respond to signals via the T cell receptor (TCR), costimulatory molecules, and immunoregulatory…sciencecityAugust 17, 2018 Read More
Publications of the Week Synthetic Microbe Communities Provide Internal Reference Standards for Metagenome Sequencing and AnalysisHardwick, S.A., et al. | August 15, 2018The complexity of microbial communities, combined with technical biases in next-generation sequencing, pose a challenge…sciencecityAugust 15, 2018 Read More
Publications of the Week New Tools for Syphilis ResearchAuthor: Sheila Lukehart | August 10, 2018Syphilis research has been severely limited by the necessity to propagate Treponema pallidumin vivo in rabbits. After…sciencecityAugust 10, 2018 Read More
Publications of the Week Iodide Improves Outcome After Acute Myocardial Infarction in Rats and PigsFirst Author: Michael Morrison | Senior Author: Mark Roth | August 8, 2018In this study, we tested whether iodide would reduce heart damage in rat and pig…sciencecityAugust 8, 2018 Read More
Publications of the Week A Phosphatidylinositol 3-Kinase Effector Alters Phagosomal Maturation to Promote Intracellular Growth of FrancisellaFirst Author: Hannah Ledvina | Senior Author: Joseph Mougous | August 6, 2018Many pathogenic intracellular bacteria manipulate the host phago-endosomal system to establish and maintain a permissive…sciencecityAugust 6, 2018 Read More