Publications of the Week High Prevalence and Disease Correlation of Autoantibodies against p40 Encoded by Long Interspersed Nuclear Elements (LINE-1) in Systemic Lupus ErythematosusCarter, V., et al. | August 5, 2019This paper describes evidence that a retroelement in our genome, called LINE-1, is active in…sciencecityAugust 5, 2019 Read More
Publications of the Week A Pro-Inflammatory CD8+ T-Cell Subset Patrols the Cervicovaginal TractPattacini, L., et al. | August 1, 2019The immune system of the cervicovaginal tract (CVT) must balance immunosurveillance and active immunity against…sciencecityAugust 1, 2019 Read More
Publications of the Week DUX4 Suppresses MHC Class I to Promote Cancer Immune Evasion and Resistance to Checkpoint BlockadeChew, G., et al. | July 30, 2019Advances in cancer immunotherapies make it critical to identify genes that modulate antigen presentation and…sciencecityJuly 30, 2019 Read More
Publications of the Week Human CD4+CD103+ Cutaneous Resident Memory T Cells are Found in the Circulation of Healthy IndividualsKlicznik, M.M., et al. | July 26, 2019Although T cells are abundant in the blood, these circulating T cells are not thought…sciencecityJuly 26, 2019 Read More
Publications of the Week Reprogramming Identifies Functionally Distinct Stages of Clonal Evolution in Myelodysplastic SyndromesHsu, J., et al. | July 24, 2019The authors show that episomal reprogramming of MDS and AML patient samples to iPSCs captures…sciencecityJuly 24, 2019 Read More
Publications of the Week Controlling Protein Assembly on Inorganic Crystals through Designed Protein InterfacesPyles, H., et al. | July 22, 2019Many hard biomaterials like bone and teeth get their exquisite material properties from protein–mineral interactions.…sciencecityJuly 22, 2019 Read More
Publications of the Week Human 5′ UTR Design and Variant Effect Prediction from a Massively Parallel Translation AssaySample, P.J., et al. | July 19, 2019There are two main applications for this work. First, the scientists can use their models…sciencecityJuly 19, 2019 Read More
Publications of the Week Genetic Variation, Comparative Genomics, and the Diagnosis of DiseaseEvan Eichler | July 17, 2019The genome is not akin to a string of fixed length. Many large segments of…sciencecityJuly 17, 2019 Read More
Publications of the Week Pandemic Fluoroquinolone Resistant Escherichia coli Clone ST1193 Emerged via Simultaneous Homologous Recombinations in 11 Gene LociTchesnokova, V., et al. | July 15, 2019This research shows that pandemic multi-drug resistant (‘superbug’) strains can emerge virtually instantly, without a…sciencecityJuly 15, 2019 Read More
Publications of the Week Fasting Prevents Hypoxia-Induced Defects of Proteostasis in C. ElegansIranon, N.N., et al. | July 10, 2019Low oxygen conditions (hypoxia) can impair essential physiological processes and cause cellular damage and death.…sciencecityJuly 10, 2019 Read More