Publications of the Week Targeting the Perivascular Niche Sensitizes Disseminated Tumour Cells to ChemotherapyCarlson, P., et al. | February 8, 2019The presence of disseminated tumour cells (DTCs) in bone marrow is predictive of poor metastasis-free…sciencecityFebruary 8, 2019 Read More
Publications of the Week Characterizing the Major Structural Variant Alleles of the Human GenomeAudano, P.A., et al. | February 6, 2019In order to provide a comprehensive resource for human structural variants (SVs), we generated long-read…sciencecityFebruary 6, 2019 Read More
Publications of the Week Basophil-Derived Tumor Necrosis Factor Can Enhance Survival in a Sepsis Model in MiceScience in Seattle | February 4, 2019Our publication in Nature Immunology revealed how a rare group of white blood cells called basophils play…sciencecityFebruary 4, 2019 Read More
Publications of the Week CIRCling the Wagons to Protect Intestinal Stem CellsSoveg, F., et al. | February 1, 2019The epithelium of the small intestine is tasked with balancing its role of absorbing nutrients…sciencecityFebruary 1, 2019 Read More
Publications of the Week Chronic TLR7 and TLR9 Signaling Drives Anemia via Differentiation of Specialized HemophagocytesAkilesh, H.M., et al. | January 30, 2019Read the Publication This week we profile a recent publication in Science from Dr. Jessica…sciencecityJanuary 30, 2019 Read More
Publications of the Week The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in NeuronsDaniels, B.P., et al. | January 28, 2019My lab has been focused on programmed cell death, and on how the immune system…sciencecityJanuary 28, 2019 Read More
Publications of the Week Glycan Targeted Polymeric Antibiotic Prodrugs for Alveolar Macrophage InfectionsChen, J., et al. | January 25, 2019Alveolar macrophages resident in the lung are prominent phagocytic effector cells of the pulmonary innate…sciencecityJanuary 25, 2019 Read More
Publications of the Week A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic ScreensGasperini, M., et al. | January 24, 2019Over one million candidate regulatory elements have been identified across the human genome, but nearly…sciencecityJanuary 24, 2019 Read More
Publications of the Week Cumulative Mitochondrial Activity Correlates with Ototoxin Susceptibility in Zebrafish Mechanosensory Hair CellsPickett, S.B., et al. | January 18, 2019Mitochondria play a prominent role in mechanosensory hair cell damage and death. Although hair cells…sciencecityJanuary 18, 2019 Read More
Publications of the Week Nanoscavenger Provides Long-Term Prophylactic Protection against Nerve Agents in RodentsZhang, P., et al. | January 14, 2019Nerve agents are a class of organophosphorus compounds (OPs) that blocks communication between nerves and…sciencecityJanuary 14, 2019 Read More