Publications of the Week Separate Polycomb Response Elements Control Chromatin State and Activation of the Vestigial Gene Ahmad K., and Spens, A.E. | September 6, 2019 Polycomb-based gene silencing is a central chromatin-based mechanism for shutting off genes during cell fate…sciencecitySeptember 6, 2019 Read More
Publications of the Week Discriminative T Cell Recognition of Cross-Reactive Islet-Antigens Is Associated with HLA-DQ8 Transdimer–Mediated Autoimmune Diabetes Chow, I., et al. | September 3, 2019 This publication made a key discovery about the structural and functional characteristics of T cells…sciencecitySeptember 3, 2019 Read More
Publications of the Week Defined Neuronal Populations Drive Fatal Phenotype in a Mouse Model of Leigh Syndrome Bolea, I., et al. | August 30, 2019 The authors studied different new mouse models that have mitochondrial dysfunction only in specific groups…sciencecityAugust 30, 2019 Read More
Publications of the Week Prebiotic Amino Acids Bind to and Stabilize Prebiotic Fatty Acid Membranes Cornell, C.E., et al. | August 28, 2019 How did the first cells on Earth arise? In a minimal cell, a membrane separates…sciencecityAugust 28, 2019 Read More
Publications of the Week STING Is Required for Host Defense against Neuropathological West Nile Virus Infection Wuertz, K.M., et al. | August 26, 2019 West Nile Virus (WNV), an emerging and re-emerging RNA virus, is the leading source of…sciencecityAugust 26, 2019 Read More
Publications of the Week RIG-I-Like Receptors Direct Inflammatory Macrophage Polarization against West Nile Virus Infection Stone, A.E.L, et al. | August 23, 2019 RIG-I-Like Receptors (RLRs) RIG-I, MDA5, and LGP2, are vital pathogen recognition receptors in the defense…sciencecityAugust 23, 2019 Read More
Publications of the Week Autophosphorylation Is Sufficient to Release Mps1 Kinase from Native Kinetochores Koch, L.B., et al. | August 22, 2019 If even a single chromosome is unattached or incorrectly attached, an enzyme, Mps1, initiates checkpoint…sciencecityAugust 22, 2019 Read More
Publications of the Week Detection and Activation of HIV Broadly Neutralizing Antibody Precursor B Cells Using Anti-Idiotypes Bancroft, T., et al. | August 19, 2019 The authors merged an old technology, anti-idiotypes, showing that it could be paired with newer…sciencecityAugust 19, 2019 Read More
Publications of the Week Epicardial Cells Derived from Human Embryonic Stem Cells Augment Cardiomyocyte-Driven Heart Regeneration Bargehr, J., et al. | August 16, 2019 The authors previously showed that transplanting human heart muscle cells into myocardial infarcts resulted in…sciencecityAugust 16, 2019 Read More
Publications of the Week Therapeutically Relevant Engraftment of a CRISPR-Cas9–Edited HSC-Enriched Population with HbF Reactivation in Nonhuman Primates Humbert, O., et al. | August 14, 2019 The CRISPR/Cas9 technology offers many opportunities to treat genetic and infectious diseases, but safety of…sciencecityAugust 14, 2019 Read More