Publications of the Week Evidence for Minimal Cardiogenic Potential of Stem Cell Antigen 1–Positive Cells in the Adult Mouse HeartNeidig, L.E., et al. | January 3, 2019De novo cardiomyogenesis is limited to ≈1% per year in the adult mammalian heart.1 Whether newly…sciencecityJanuary 3, 2019 Read More
Publications of the Week Programmable Design of Orthogonal Protein HeterodimersChen, Z., et al. | January 2, 2019Specificity of interactions between two DNA strands, or between protein and DNA, is often achieved…sciencecityJanuary 2, 2019 Read More
Publications of the Week An Ultra-High Affinity Ligand of HIV-1 TAR Reveals the RNA Structure Recognized By P-TEFbShortridge, M.D., et al. | December 13, 2018The HIV-1 trans-activator protein Tat binds the trans-activation response element (TAR) to facilitate recruitment of the…sciencecityDecember 13, 2018 Read More
Publications of the Week Clinical Potential of Mass Spectrometry-Based ProteogenomicsZhang, B., et al. | December 10, 2018Cancer genomics research aims to advance personalized oncology by finding and targeting specific genetic alterations…sciencecityDecember 10, 2018 Read More
Publications of the Week The RecB Helicase-Nuclease Tether Mediates Chi Hotspot Control of RecBCD EnzymeAmundsen, S.K., et al. | December 5, 2018Our lab studies DNA break repair and genetic recombination in bacteria (E. coli) and fission…sciencecityDecember 5, 2018 Read More
Publications of the Week Structural Plasticity of D3-D14 Ubiquitin Ligase in Strigolactone SignallingShabek, N., et al. | December 3, 2018One major focus of our research is to understand the role of selective protein destruction…sciencecityDecember 3, 2018 Read More
Publications of the Week Gene Inversion Potentiates Bacterial Evolvability and VirulenceMerrikh, C.N., et al. | November 30, 2018The research in Houra Merrikh’s lab is focused on bacterial DNA replication, repair, mutagenesis, and…sciencecityNovember 30, 2018 Read More
Publications of the Week Cytokine Release Syndrome and Neurotoxicity After CD19 Chimeric Antigen Receptor-Modified (CAR-) T Cell TherapyHay, K.A. | November 28, 2018Chimeric antigen receptor-modified (CAR)-T cells have demonstrated impressive results in the treatment of haematological malignancies.…sciencecityNovember 28, 2018 Read More
Publications of the Week Structure, Subunit Organization and Behavior of the Asymmetric Type IIT Restriction Endonuclease BbvCIShen, B.W., et al. | November 27, 2018BbvCI, a Type IIT restriction endonuclease, recognizes and cleaves the seven base pair sequence 5'-CCTCAGC-3',…sciencecityNovember 27, 2018 Read More
Publications of the Week A Bifunctional Role for the UHRF1 UBL Domain in the Control of Hemi-Methylated DNA-Dependent Histone UbiquitylationDaRosa, P.A., et al. | November 23, 2018This publication reports on the structural mechanism by methylated CpG motifs are maintained following DNA…sciencecityNovember 23, 2018 Read More