Publications of the Week Structural Plasticity of D3-D14 Ubiquitin Ligase in Strigolactone Signalling Shabek, N., et al. | December 3, 2018 One major focus of our research is to understand the role of selective protein destruction…sciencecityDecember 3, 2018 Read More
Publications of the Week Gene Inversion Potentiates Bacterial Evolvability and Virulence Merrikh, C.N., et al. | November 30, 2018 The research in Houra Merrikh’s lab is focused on bacterial DNA replication, repair, mutagenesis, and…sciencecityNovember 30, 2018 Read More
Publications of the Week Cytokine Release Syndrome and Neurotoxicity After CD19 Chimeric Antigen Receptor-Modified (CAR-) T Cell Therapy Hay, K.A. | November 28, 2018 Chimeric antigen receptor-modified (CAR)-T cells have demonstrated impressive results in the treatment of haematological malignancies.…sciencecityNovember 28, 2018 Read More
Publications of the Week Structure, Subunit Organization and Behavior of the Asymmetric Type IIT Restriction Endonuclease BbvCI Shen, B.W., et al. | November 27, 2018 BbvCI, a Type IIT restriction endonuclease, recognizes and cleaves the seven base pair sequence 5'-CCTCAGC-3',…sciencecityNovember 27, 2018 Read More
Publications of the Week A Bifunctional Role for the UHRF1 UBL Domain in the Control of Hemi-Methylated DNA-Dependent Histone Ubiquitylation DaRosa, P.A., et al. | November 23, 2018 This publication reports on the structural mechanism by methylated CpG motifs are maintained following DNA…sciencecityNovember 23, 2018 Read More
Publications of the Week Oncogenic Activation of PI3K Induces Progenitor Cell Differentiation to Suppress Epidermal Growth Zhe, Y., et al. | November 21, 2018 Our recent work discovered stem cell differentiation as the primary block to oncogene-driven clonal expansion…sciencecityNovember 21, 2018 Read More
Publications of the Week h-Channels Contribute to Divergent Intrinsic Membrane Properties of Supragranular Pyramidal Neurons in Human Versus Mouse Cerebral Cortex Kalmbach, B.E., et al. | November 19, 2018 Human and rodent brains are clearly different in terms of size and complexity. Yet, how…sciencecityNovember 19, 2018 Read More
Publications of the Week Dormant Tumor Cells, Their Niches and the Influence of Immunity Goddard, E.T., et al. | November 15, 2018 Despite increased focus on the clinical relevance of dormant metastatic disease, our understanding of dormant…sciencecityNovember 15, 2018 Read More
Publications of the Week De Novo Design of a Non-Local β-Sheet Protein with High Stability and Accuracy Marcos, E., et al. | November 13, 2018 Natural proteins evolved over billions of years to solve biology’s most complex problems. But we…sciencecityNovember 13, 2018 Read More
Publications of the Week Parabrachial CGRP Neurons Establish and Sustain Aversive Taste Memories Chen, J.Y., et al. | November 9, 2018 Food aversions develop when the taste of a novel food is associated with sickness, which…sciencecityNovember 9, 2018 Read More