Publications of the Week A Whole-Slide Foundation Model for Digital Pathology from Real-World Data Xu, H., et al. | May 30, 2024 Digital pathology poses unique computational challenges, as a standard gigapixel slide may comprise tens of…karnottMay 30, 2024 Read More
Publications of the Week Gene Editing for Latent Herpes Simplex Virus Infection Reduces Viral Load and Shedding In Vivo Aubert, M., et al. | May 21, 2024 Anti-HSV therapies are only suppressive because they do not eliminate latent HSV present in ganglionic…karnottMay 21, 2024 Read More
Publications of the Week Computational Design of Non-Porous pH-Responsive Antibody Nanoparticles Yang, E., et al. | May 20, 2024 Programming protein nanomaterials to respond to changes in environmental conditions is a current challenge for…karnottMay 20, 2024 Read More
Publications of the Week A Phase 2 Randomized Trial with Autologous Polyclonal Expanded Regulatory T Cells in Children with New-Onset Type 1 Diabetes Bender, C., et al. | May 17, 2024 This week we profile a recent publication in Science Translational Medicine by Drs. Christine Bender…karnottMay 17, 2024 Read More
Publications of the Week Mutation Patterns Predict Drug Sensitivity in Acute Myeloid Leukemia Qin, G., et al. | May 14, 2024 The inherent genetic heterogeneity of acute myeloid leukemia (AML) has challenged the development of precise…karnottMay 14, 2024 Read More
Publications of the Week Removal of Exogenous Stimuli Reveals a Canalization of Circadian Physiology in a Vertically Migrating Copepod Timmins-Schiffman, E., et al. | May 9, 2024 Diel rhythms are observed across taxa and are important for maintaining synchrony between the environment…karnottMay 9, 2024 Read More
Publications of the Week The Diverse Evolutionary Histories of Domesticated Metaviral Capsid Genes in Mammals | May 6, 2024 Selfish genetic elements comprise significant fractions of mammalian genomes. In rare instances, host genomes domesticate…karnottMay 6, 2024 Read More
Publications of the Week Interleukin-4 Downregulates Transcription Factor BCL6 to Promote Memory B Cell Selection in Germinal Centers Shehata, L., et al. | May 2, 2024 Researchers showed that IL-4 cytokine signaling in GC B cells directly downregulated the transcription factor…pthomsonMay 2, 2024 Read More
Publications of the Week Distributed X Chromosome Inactivation in Brain Circuitry Is Associated with X-linked Disease Penetrance of Behavior Szelenyi, E., et al. | April 30, 2024 The precise anatomical degree of brain X chromosome inactivation (XCI) that is sufficient to alter…karnottApril 30, 2024 Read More
Publications of the Week Parabrachial Calca Neurons Drive Nociplasticity Condon, L., et al. | April 30, 2024 Pain that persists beyond the time required for tissue healing and pain that arises in…karnottApril 30, 2024 Read More