Gene drives are genetic modifications designed to propagate efficiently through a population. Most applications rely…
karnottOctober 18, 2024
The aim of this work was to explore molecular amino acids (AAs) and related structures…
karnottOctober 4, 2024
The Cytochrome P450s (CYPs) enzyme family metabolizes ∼80% of small molecule drugs. Variants in CYPs…
karnottSeptember 27, 2024
Diabetes increases the risk of both cardiovascular disease and kidney disease. Notably, most of the…
karnottSeptember 18, 2024
Resource partitioning is central to the incredible productivity of microbial communities, including gigatons in annual…
karnottSeptember 12, 2024
In silico variant effect predictions are available for nearly all missense variants but played a…
karnottSeptember 10, 2024
Antibody inhibitors pose an ongoing challenge to the treatment of subjects with inherited protein deficiency…
karnottSeptember 6, 2024
Protein–protein interactions (PPIs) regulate many cellular processes and engineered PPIs have cell and gene therapy…
karnottSeptember 4, 2024
RIT1 is a rare and understudied oncogene in lung cancer. Despite structural similarity to other…
karnottAugust 28, 2024
