Publications of the Week Improving the Secretion of Designed Protein Assemblies Through Negative Design of Cryptic Transmembrane DomainsWang, J.Y.J., et al. | March 15, 2023Computationally designed protein nanoparticles have recently emerged as a promising platform for the development of…sciencecityMarch 15, 2023 Read More
Publications of the Week A Chemically Controlled Cas9 Switch Enables Temporal Modulation of Diverse EffectorsWei, C.T., et al. | March 14, 2023CRISPR-Cas9 has yielded a plethora of effectors, including targeted transcriptional activators, base editors and prime…sciencecityMarch 14, 2023 Read More
Publications of the Week Linking Connectome with Transcriptome Using a Self-Inactivating Rabies VirusYao, S. and Levi, B.P. | March 8, 2023Genetically engineered rabies virus is a powerful tool for investigating the structure and function of…sciencecityMarch 8, 2023 Read More
Publications of the Week Automatic and Accurate Ligand Structure Determination Guided by Cryo-Electron Microscopy MapsMuenks, A., et al. | March 6, 2023Advances in cryo-electron microscopy (cryoEM) and deep-learning guided protein structure prediction have expedited structural studies…sciencecityMarch 6, 2023 Read More
Publications of the Week Reversible Epigenetic Alterations Mediate PSMA Expression Heterogeneity in Advanced Metastatic Prostate CancerSayer, E., et al. | March 1, 2023Prostate-specific membrane antigen (PSMA) is an important cell surface target in prostate cancer. There are…pthomsonMarch 1, 2023 Read More
Publications of the Week MUC5AC Genetic Variation Is Associated with Tuberculous Meningitis CSF Cytokine Responses and MortalitySabo, M. C., et al. | February 28, 2023Independent SNPs in MUC5B and MUC5AC (genotyped by Illumina HumanOmniExpress array) were assessed for associations with TNF concentrations (measured…pthomsonFebruary 28, 2023 Read More
Publications of the Week ATP Is a Major Determinant of Phototrophic Bacterial Longevity in Growth ArrestYin, L., et al. | February 22, 2023How bacteria transition into growth arrest as part of stationary phase has been well-studied, but…sciencecityFebruary 22, 2023 Read More
Publications of the Week Cross-Protective Antibodies against Common Endemic Respiratory VirusesCabán, M., et al. | February 21, 2023Respiratory syncytial virus (RSV), human metapneumovirus (HMPV), and human parainfluenza virus types one (HPIV1) and…sciencecityFebruary 21, 2023 Read More
Publications of the Week Anti-HLA Antibodies in Recipients of CD19 versus BCMA-Targeted Car T-Cell TherapyHill, J.A., et al. | February 15, 2023Antibodies against foreign human leukocyte antigen (HLA) molecules are barriers to successful organ transplantation. B…sciencecityFebruary 15, 2023 Read More
Publications of the Week A Virus-Packageable CRISPR System Identifies Host Dependency Factors Co-Opted by Multiple HIV-1 StrainsMontoya, V.R., et al. | February 14, 2023At each stage of the HIV life cycle, host cellular proteins are hijacked by the…sciencecityFebruary 14, 2023 Read More