Publications of the Week SRC Inhibition Enables Formation of a Growth Suppressive MAGI1-PP2A Complex in Isocitrate Dehydrogenase-Mutant Cholangiocarcinoma Luk, I., et al. | June 12, 2024 In intrahepatic cholangiocarcinoma (ICC), mutations in the genes encoding isocitrate dehydrogenase (IDH) lead to dependence…karnottJune 12, 2024 Read More
Publications of the Week Antigen-Level Resolution of Commensal-Specific B Cell Responses Can Be Enabled by Phage Display Screening Coupled with B Cell Tetramers Verma, S., et al. | June 10, 2024 Induction of commensal-specific immunity contributes to tissue homeostasis, yet the mechanisms underlying induction of commensal-specific…karnottJune 10, 2024 Read More
Publications of the Week Macroscopic Changes in Aquaporin-4 Underlie Blast Traumatic Brain Injury-Related Impairment in Glymphatic Function Braun, M., et al. | June 5, 2024 Mild traumatic brain injury (mTBI) has emerged as a potential risk factor for the development…karnottJune 5, 2024 Read More
Publications of the Week One-Step Purification and N-Terminal Functionalization of Bioactive Proteins via Atypically Split Inteins | June 4, 2024 Site-specific installation of non-natural functionality onto proteins has enabled countless applications in biotechnology, chemical biology,…karnottJune 4, 2024 Read More
Publications of the Week Simple Behavioral Analysis (SimBA) as a Platform for Explainable Machine Learning in Behavioral Neuroscience Goodwin, N., et al. | May 31, 2024 The study of complex behaviors is often challenging when using manual annotation due to the…karnottMay 31, 2024 Read More
Publications of the Week A Whole-Slide Foundation Model for Digital Pathology from Real-World Data Xu, H., et al. | May 30, 2024 Digital pathology poses unique computational challenges, as a standard gigapixel slide may comprise tens of…karnottMay 30, 2024 Read More
Publications of the Week Gene Editing for Latent Herpes Simplex Virus Infection Reduces Viral Load and Shedding In Vivo Aubert, M., et al. | May 21, 2024 Anti-HSV therapies are only suppressive because they do not eliminate latent HSV present in ganglionic…karnottMay 21, 2024 Read More
Publications of the Week Computational Design of Non-Porous pH-Responsive Antibody Nanoparticles Yang, E., et al. | May 20, 2024 Programming protein nanomaterials to respond to changes in environmental conditions is a current challenge for…karnottMay 20, 2024 Read More
Publications of the Week A Phase 2 Randomized Trial with Autologous Polyclonal Expanded Regulatory T Cells in Children with New-Onset Type 1 Diabetes Bender, C., et al. | May 17, 2024 This week we profile a recent publication in Science Translational Medicine by Drs. Christine Bender…karnottMay 17, 2024 Read More
Publications of the Week Mutation Patterns Predict Drug Sensitivity in Acute Myeloid Leukemia Qin, G., et al. | May 14, 2024 The inherent genetic heterogeneity of acute myeloid leukemia (AML) has challenged the development of precise…karnottMay 14, 2024 Read More