Publications of the Week Spike Deep Mutational Scanning Helps Predict Success of SARS-CoV-2 Clades Dadonaite, B., et al. | July 3, 2024 SARS-CoV-2 variants acquire mutations in the spike protein that promote immune evasion1 and affect other…karnottJuly 3, 2024 Read More
Publications of the Week Microbial Community-Scale Metabolic Modelling Predicts Personalized Short-Chain Fatty Acid Production Profiles in the Human Gut Quinn-Bohmann, N., et al. | June 27, 2024 Microbially derived short-chain fatty acids (SCFAs) in the human gut are tightly coupled to host…karnottJune 27, 2024 Read More
Publications of the Week High-Throughput Single-Cell Transcriptomics of Bacteria Using Combinatorial Barcoding Gaisser, K., et al. | June 26, 2024 Microbial split-pool ligation transcriptomics (microSPLiT) is a high-throughput single-cell RNA sequencing method for bacteria. With…karnottJune 26, 2024 Read More
Publications of the Week Inverted Triplications Formed by Iterative Template Switches Generate Structural Variant Diversity at Genomic Disorder Loci Grochowski, C., et al. | June 24, 2024 The duplication-triplication/inverted-duplication (DUP-TRP/INV-DUP) structure is a complex genomic rearrangement (CGR). Although it has been identified…karnottJune 24, 2024 Read More
Publications of the Week Germline-like TCR-α Chains Shared between Autoreactive T Cells in Blood and Pancreas Linsley, P.S., et al. | June 20, 2024 Human type 1 diabetes (T1D) is caused by autoimmune attack on the insulin-producing pancreatic beta…sciencecityJune 20, 2024 Read More
Publications of the Week Modulation of FGF Pathway Signaling and Vascular Differentiation Using Designed Oligomeric Assemblies Edman, N.I., et al. | June 18, 2024 Many growth factors and cytokines signal by binding to the extracellular domains of their receptors…sciencecityJune 18, 2024 Read More
Publications of the Week Rho-Associated Kinase Regulates Langerhans Cell Morphology and Responsiveness to Tissue Damage Peterman, E., et al. | June 14, 2024 Skin damage requires efficient immune cell responses to restore organ function. Epidermal-resident immune cells known…karnottJune 14, 2024 Read More
Publications of the Week SRC Inhibition Enables Formation of a Growth Suppressive MAGI1-PP2A Complex in Isocitrate Dehydrogenase-Mutant Cholangiocarcinoma Luk, I., et al. | June 12, 2024 In intrahepatic cholangiocarcinoma (ICC), mutations in the genes encoding isocitrate dehydrogenase (IDH) lead to dependence…karnottJune 12, 2024 Read More
Publications of the Week Antigen-Level Resolution of Commensal-Specific B Cell Responses Can Be Enabled by Phage Display Screening Coupled with B Cell Tetramers Verma, S., et al. | June 10, 2024 Induction of commensal-specific immunity contributes to tissue homeostasis, yet the mechanisms underlying induction of commensal-specific…karnottJune 10, 2024 Read More
Publications of the Week Macroscopic Changes in Aquaporin-4 Underlie Blast Traumatic Brain Injury-Related Impairment in Glymphatic Function Braun, M., et al. | June 5, 2024 Mild traumatic brain injury (mTBI) has emerged as a potential risk factor for the development…karnottJune 5, 2024 Read More