Publications of the Week Bladder Cancer Patient-Derived Organoids and Avatars for Personalized Cancer DiscoverySoo Kim, Y., Hsieh, A. C., and Lam, H. M. | August 16, 2022Prediction of treatment response has attracted growing attention in cancer research to improve clinical outcomes…dcorriganAugust 16, 2022 Read More
Publications of the Week Discovery of a Transferrin Receptor 1-Binding Aptamer and Its Application in Cancer Cell Depletion for Adoptive T Cell Therapy ManufacturingCheng, E. L., et al. | August 12, 2022The authors report a new high-affinity aptamer that binds to the transferrin receptor, also called…dcorriganAugust 12, 2022 Read More
Publications of the Week Breath of Fresh Air: Towards Unraveling the Molecular Underpinnings of Sleep Apnea | August 12, 2022Obstructive sleep apnea (OSA) is an important risk factor for multiple diseases (1). 425 million…dcorriganAugust 12, 2022 Read More
Publications of the Week Sustained Inhibition of NPY/AgRP Neuronal Activity by FGF1Hwang, E., et al. | August 5, 2022In rodent models of type 2 diabetes (T2D), central administration of fibroblast growth factor 1…dcorriganAugust 5, 2022 Read More
Publications of the Week An In Vivo Model of Human Macrophages in Metastatic MelanomaVoillet, V., et al. | August 4, 2022Despite recent therapeutic progress, advanced melanoma remains lethal for many patients. The composition of the…dcorriganAugust 4, 2022 Read More
Publications of the Week Intraosseous Delivery of Platelet-Targeted FVIII Lentiviral Vector in Humanized NBSGW MiceHoyoung Joo, J., et al. | July 29, 2022Read the Publication This week we profile a recent publication in Blood Advances from the…dcorriganJuly 29, 2022 Read More
Publications of the Week Pharmacological Targeting of TFIIH Suppresses KRAS Mutant Pancreatic Ductal Adenocarcinoma and Synergizes with TRAILMoser, R., et al. | July 29, 2022Pancreatic ductal adenocarcinoma (PDAC) typically presents as metastatic disease at diagnosis and remains refractory to…dcorriganJuly 29, 2022 Read More
Publications of the Week Mucosal Viral Infection Induces a Regulatory T Cell Activation Phenotype Distinct from Tissue Residency in Mouse and Human TissuesTraxinger, B. R., et al. | July 21, 2022The authors' work contributes to a growing research body on mucosal tissue regulatory T cells…dcorriganJuly 21, 2022 Read More
Publications of the Week TOLLIP Optimizes Dendritic Cell Maturation to Lipopolysaccharide and Mycobacterium tuberculosisVenkatasubramanian, S., et al. | July 19, 2022The authors found that TOLLIP, a gene associated with TB susceptibility, influences dendritic cell maturation,…dcorriganJuly 19, 2022 Read More
Publications of the Week A Slow Dynamic RNA Switch Regulates Processing of microRNA-21Shortridge, M. D., et al. | July 15, 2022The microRNAs are non-coding RNAs which post-transcriptionally regulate the expression of many eukaryotic genes, and whose dysregulation…dcorriganJuly 15, 2022 Read More