Publications of the Week T Cell Receptor Sequences Are the Dominant Factor Contributing to the Phenotype of CD8+ T Cells with Specificities Against Immunogenic Viral Antigens Chen, D., et al. | November 24, 2023 This week, Science in Seattle profiles Dr. Jim Heath (pictured). Dr. Heath is President and…karnottNovember 24, 2023 Read More
Publications of the Week Probing Cerebral Malaria Inflammation in 3D Human Brain Microvessels Howard, C., et al. | November 23, 2023 Sequestration of Plasmodium falciparum-infected erythrocytes (IEs) in the brain microcirculation is a hallmark of cerebral…karnottNovember 23, 2023 Read More
Publications of the Week Embryo-Scale Reverse Genetics at Single-Cell Resolution Saunders, L., et al. | November 22, 2023 The maturation of single-cell transcriptomic technologies has facilitated the generation of comprehensive cellular atlases from…karnottNovember 22, 2023 Read More
Publications of the Week Inter-alpha Inhibitor Proteins Attenuate Lipopolysaccharide-Induced Blood-Brain Barrier Disruption in Neonatal Mice Logsdon, A., et al. | November 17, 2023 There is a paucity of information regarding efficacious pharmacological neuroprotective strategies to attenuate or reduce…sciencecityNovember 17, 2023 Read More
Publications of the Week Single-Cell, Whole-Embryo Phenotyping of Mammalian Developmental Disorders Huang, X., et al. | November 16, 2023 Mouse models are a critical tool for studying human diseases, particularly developmental disorders. However, conventional…sciencecityNovember 16, 2023 Read More
Publications of the Week A Novel Formulation Enabled Transformation of 3-HIV Drugs Tenofovir–Lamivudine–Dolutegravir from Short-Acting to Long-Acting All-in-One Injectable Perazzolo, S., et al. | November 10, 2023 To develop an injectable dosage form of the daily oral HIV drugs, tenofovir (T), lamivudine…sciencecityNovember 10, 2023 Read More
Publications of the Week Induction of Long-Term Tolerance to a Specific Antigen Using Anti-CD3 Lipid Nanoparticles Following Gene Therapy Chen, C., et al. | November 8, 2023 Development of factor VIII (FVIII) inhibitors is a serious complication in the treatment of hemophilia…sciencecityNovember 8, 2023 Read More
Publications of the Week Structural Basis for Severe Pain Caused by Mutations in the Voltage Sensors of Sodium Channel NaV1.7 Wisedchaisri, G., et al. | November 3, 2023 Voltage-gated sodium channels in peripheral nerves conduct nociceptive signals from nerve endings to the spinal…sciencecityNovember 3, 2023 Read More
Publications of the Week Efficient Long-Term Multilineage Engraftment of CD33-Edited Hematopoietic Stem/Progenitor Cells in Nonhuman Primates Petty, N., et al. | November 2, 2023 Current immunotherapeutic targets are often shared between neoplastic and normal hematopoietic stem and progenitor cells…sciencecityNovember 2, 2023 Read More
Publications of the Week On the Driver of Blood Circulation Beyond the Heart Zheng, L., et al. | October 26, 2023 The heart is widely acknowledged as the unique driver of blood circulation. Recently, we discovered…sciencecityOctober 26, 2023 Read More