The authors provide some of the first evidence that large copy-number changes that originated in…
sciencecityOctober 28, 2019
SF3B1 is the most commonly mutated RNA splicing factor in cancer1,2,3,4, but the mechanisms by…
sciencecityOctober 23, 2019
The ability to expand hematopoietic stem and progenitor cells (HSPCs) ex vivo is critical to…
sciencecityOctober 21, 2019
Up to 40% of the human proteome, including human small heat shock proteins (sHSPs) and…
sciencecityOctober 17, 2019
To endure over the organismal lifespan, neurons utilize multiple strategies to achieve protein. To identify…
sciencecityOctober 15, 2019
Many of the regulatory features governing erythrocyte specification, maturation, and associated disorders remain enigmatic. To…
sciencecityOctober 11, 2019
B cell maturation antigen (BCMA) is a validated target for chimeric antigen receptor (CAR) T…
sciencecityOctober 9, 2019
While the effector pathways that mediate graft-versus-host disease (GVHD) are well established (i.e. donor T…
sciencecityOctober 7, 2019
Monosodium urate (MSU) crystals activate inflammatory pathways that overlap with interleukin-1β (IL-1β) signaling. However, the…
sciencecityOctober 3, 2019
