Publications of the Week RIG-I-Like Receptors Direct Inflammatory Macrophage Polarization against West Nile Virus Infection Stone, A.E.L, et al. | August 23, 2019 RIG-I-Like Receptors (RLRs) RIG-I, MDA5, and LGP2, are vital pathogen recognition receptors in the defense…sciencecityAugust 23, 2019 Read More
Publications of the Week Autophosphorylation Is Sufficient to Release Mps1 Kinase from Native Kinetochores Koch, L.B., et al. | August 22, 2019 If even a single chromosome is unattached or incorrectly attached, an enzyme, Mps1, initiates checkpoint…sciencecityAugust 22, 2019 Read More
Publications of the Week Detection and Activation of HIV Broadly Neutralizing Antibody Precursor B Cells Using Anti-Idiotypes Bancroft, T., et al. | August 19, 2019 The authors merged an old technology, anti-idiotypes, showing that it could be paired with newer…sciencecityAugust 19, 2019 Read More
Publications of the Week Epicardial Cells Derived from Human Embryonic Stem Cells Augment Cardiomyocyte-Driven Heart Regeneration Bargehr, J., et al. | August 16, 2019 The authors previously showed that transplanting human heart muscle cells into myocardial infarcts resulted in…sciencecityAugust 16, 2019 Read More
Publications of the Week Therapeutically Relevant Engraftment of a CRISPR-Cas9–Edited HSC-Enriched Population with HbF Reactivation in Nonhuman Primates Humbert, O., et al. | August 14, 2019 The CRISPR/Cas9 technology offers many opportunities to treat genetic and infectious diseases, but safety of…sciencecityAugust 14, 2019 Read More
Publications of the Week The Androgen Receptor Regulates a Druggable Translational Regulon in Advanced Prostate Cancer Liu, Y., et al. | August 12, 2019 Most prostate cancers are initially addicted to androgens and the androgen receptor, which they use…sciencecityAugust 12, 2019 Read More
Publications of the Week Rethinking the Role of the Brain in Glucose Homeostasis and Diabetes Pathogenesis Brown, J.M., et al. | August 9, 2019 The brain plays a major role in homeostatic processes ranging from control of body temperature…sciencecityAugust 9, 2019 Read More
Publications of the Week Epitope Targeting with Self-Assembled Peptide Vaccines Zeigler, D.F., et al. | August 7, 2019 Nanoparticle-based delivery systems are being used to simplify and accelerate new vaccine development. Previously, we…sciencecityAugust 7, 2019 Read More
Publications of the Week High Prevalence and Disease Correlation of Autoantibodies against p40 Encoded by Long Interspersed Nuclear Elements (LINE-1) in Systemic Lupus Erythematosus Carter, V., et al. | August 5, 2019 This paper describes evidence that a retroelement in our genome, called LINE-1, is active in…sciencecityAugust 5, 2019 Read More
Publications of the Week A Pro-Inflammatory CD8+ T-Cell Subset Patrols the Cervicovaginal Tract Pattacini, L., et al. | August 1, 2019 The immune system of the cervicovaginal tract (CVT) must balance immunosurveillance and active immunity against…sciencecityAugust 1, 2019 Read More