Publications of the Week The Unfolded Protein Response Components IRE1α and XBP1 Promote Human Coronavirus InfectionFink, S. L., et al. | June 13, 2023The cellular processes that support human coronavirus replication and contribute to the pathogenesis of severe…pthomsonJune 13, 2023 Read More
Publications of the Week Metrologically Traceable Quantification of 3 Apolipoprotein E Isoforms in Cerebrospinal FluidHoofnagle, A. N., et al. | June 13, 2023APOE genotype is associated with Alzheimer's disease. Thus, the concentration of apolipoprotein E (apoE) isoforms…pthomsonJune 13, 2023 Read More
Publications of the Week Analysis of Antibiotic Exposure and Development of Acute Graft-vs-Host Disease Following Allogeneic Hematopoietic Cell TransplantationRashidi, A., et al. | June 12, 2023Certain antibiotic exposures have been associated with increased rates of acute graft-vs-host disease (aGVHD) after…pthomsonJune 12, 2023 Read More
Publications of the Week Mitochondrial N-Formyl Methionine Peptides Contribute to Exaggerated Neutrophil Activation in Patients With COVID-19Kuley, R., et al. | June 7, 2023Neutrophil dysregulation is well established in COVID-19. However, factors contributing to neutrophil activation in COVID-19…sciencecityJune 7, 2023 Read More
Publications of the Week Identification of Broad, Potent Antibodies to Functionally Constrained Regions of SARS-CoV-2 Spike Following a Breakthrough InfectionGuenthoer, J., et al. | June 6, 2023The antiviral benefit of antibodies can be compromised by viral escape especially for rapidly evolving…sciencecityJune 6, 2023 Read More
Publications of the Week Several Cell-Intrinsic Effectors Drive Type I Interferon-Mediated Restriction of HIV-1 in Primary CD4+ T CellsItell, H.L., et al. | May 30, 2023Type I interferon (IFN) upregulates proteins that inhibit HIV within infected cells. Prior studies have…sciencecityMay 30, 2023 Read More
Publications of the Week A Computational Method for Cell Type-Specific Expression Quantitative Trait Loci Mapping Using Bulk RNA-Seq DataLittle, P., et al. | May 29, 2023Mapping cell type-specific gene expression quantitative trait loci (ct-eQTLs) is a powerful way to investigate…sciencecityMay 29, 2023 Read More
Publications of the Week Liver-Humanized NSG-PiZ Mice Support the Study of Chronic Hepatitis B Virus Infection and Antiviral TherapiesColón-Thillet, R., et al. | May 23, 2023Hepatitis B virus (HBV) is a pathogen of major public health importance that is largely…sciencecityMay 23, 2023 Read More
Publications of the Week Distinct Immune Responses Associated With Vaccination Status and Protection Outcomes After Malaria ChallengeOyong, D.A., et al. | May 22, 2023Understanding immune mechanisms that mediate malaria protection is critical for improving vaccine development. Vaccination with…sciencecityMay 22, 2023 Read More
Publications of the Week Integrated Analysis of Blood and Urine Biomarkers to Identify Acute Kidney Injury Subphenotypes and Associations With Long-term OutcomesBhatraju, P.K., et al. | May 19, 2023Acute kidney injury (AKI) is a heterogeneous clinical syndrome with varying causes, pathophysiology, and outcomes.…sciencecityMay 19, 2023 Read More