Publications of the Week De Novo Protein Design by Deep Network HallucinationAnishchenko, I., et al. | December 2, 2021There has been considerable recent progress in protein structure prediction using deep neural networks to…dcorriganDecember 2, 2021 Read More
Publications of the Week Mucosal Tissue Regulatory T Cells Are Integral in Balancing Immunity and Tolerance at Portals of Antigen EntryTraxinger, B. R., Richert-Spuhler, L. E., and Lund, J. M. | December 1, 2021Foxp3+ regulatory T cells (Tregs) are a subset of CD4+ T cells that exert suppressive…dcorriganDecember 1, 2021 Read More
Publications of the Week Directional Reorientation of Migrating Neutrophils Is Limited by Suppression of Receptor Input Signaling at the Cell Rear through Myosin II ActivityHadjitheodorou, A., et al. | November 26, 2021To migrate efficiently to target locations, cells must integrate receptor inputs while maintaining polarity: a…dcorriganNovember 26, 2021 Read More
Publications of the Week Molecular Basis of Immune Evasion by the Delta and Kappa SARS-CoV-2 VariantsMccallum, M., et al. | November 25, 2021Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission leads to the emergence of variants, including…dcorriganNovember 25, 2021 Read More
Publications of the Week Cross-Validation of SARS-CoV-2 Responses in Kidney Organoids and Clinical PopulationsHelms, L., et al. | November 23, 2021Using organoids, the authors discovered that SARS-CoV-2 has an exquisite ability to infect a specific…dcorriganNovember 23, 2021 Read More
Publications of the Week An Invariant Protein That Co-Localizes with VAR2CSA on Plasmodium falciparum-Infected Red Cells Binds to Chondroitin Sulfate AKeitany, G., et al. | November 19, 2021Plasmodium falciparum-infected red blood cells (iRBCs) bind and sequester in deep vascular beds, causing malaria-related…dcorriganNovember 19, 2021 Read More
Publications of the Week Whole-Genome Sequencing Association Analyses of Stroke and Its Subtypes in Ancestrally Diverse Populations From Trans-Omics for Precision Medicine ProjectHu, Y., et al. | November 16, 2021Stroke is the leading cause of death and long-term disability worldwide. Previous genome-wide association studies…dcorriganNovember 16, 2021 Read More
Publications of the Week Morphological Diversity of Single Neurons in Molecularly Defined Cell TypesPeng, H., et al. | November 11, 2021Dendritic and axonal morphology reflects the input and output of neurons and is a defining…dcorriganNovember 11, 2021 Read More
Publications of the Week F-Domain Valency Determines Outcome of Signaling through the Angiopoietin PathwayZhao, Y. T., et al. | November 9, 2021The authors found that the valency of Ang1's receptor-binding domain, F-domain determines Tie2 signaling outcome…dcorriganNovember 9, 2021 Read More
Publications of the Week Human Parainfluenza Virus Evolution during Lung Infection of Immunocompromised Humans Promotes Viral PersistenceGreninger, A. L., et al. | November 8, 2021The capacity of respiratory viruses to undergo evolution within the respiratory tract raises the possibility…dcorriganNovember 8, 2021 Read More