Publications of the Week Single-Cell ATAC-Seq of Fetal Human Retina and Stem-Cell-Derived Retinal Organoids Shows Changing Chromatin Landscapes during Cell Fate AcquisitionFinkbeiner, C., et al. | February 7, 2022The authors used a relatively new technique, single-cell ATACseq, to reveal the transcriptional networks that…dcorriganFebruary 7, 2022 Read More
Publications of the Week A Conditioned Place Preference for Heroin Is Signaled by Increased Dopamine and Direct Pathway Activity and Decreased Indirect Pathway Activity in the Nucleus AccumbensO'Neal, T. J., et al. | February 3, 2022The authors were able to identify the neural circuits in the brain that encode the…dcorriganFebruary 3, 2022 Read More
Publications of the Week Three FDA-Approved Therapies for Chronic GVHDZeiser, R. and Lee, S. J. | February 2, 2022Chronic graft-versus-host disease (cGVHD) is a major immunological complication of allogeneic hematopoietic cell transplantation. Chronic…dcorriganFebruary 2, 2022 Read More
Publications of the Week Two Diphosphorylated Degrons Control C-Myc Degradation by the Fbw7 Tumor SuppressorWelcker, M., et al. | February 1, 2022c-Myc (hereafter, Myc) is a cancer driver whose abundance is regulated by the SCFFbw7 ubiquitin ligase…dcorriganFebruary 1, 2022 Read More
Publications of the Week Preimmunization Correlates of Protection Shared across Malaria Vaccine Trials in AdultsNeal, M. L., et al. | January 31, 2022Identifying preimmunization biological characteristics that promote an effective vaccine response offers opportunities for illuminating the…dcorriganJanuary 31, 2022 Read More
Publications of the Week A Conditioned Place Preference for Heroin Is Signaled by Increased Dopamine and Direct Pathway Activity and Decreased Indirect Pathway Activity in the Nucleus AccumbensO'Neal, T. J., et al. | January 28, 2022Repeated pairing of a drug with a neutral stimulus, such as a cue or context,…dcorriganJanuary 28, 2022 Read More
Publications of the Week Fewer LAG-3+ T Cells in Relapsing-Remitting Multiple Sclerosis and Type 1 DiabetesJones, B. E., et al. | January 26, 2022Dr. Jane Buckner’s laboratory focuses on identifying the underlying mechanisms by which the adaptive immune…dcorriganJanuary 26, 2022 Read More
Publications of the Week The Metabolome as a Biomarker of Aging in Drosophila melanogasterZhao, X., et al. | January 20, 2022Many biomarkers have been shown to be associated not only with chronological age but also…dcorriganJanuary 20, 2022 Read More
Publications of the Week Whole-Blood Cytokine Secretion Assay as a High-Throughput Alternative for Assessing the Cell-Mediated Immunity Profile after Two Doses of an Adjuvanted SARS-CoV-2 Recombinant Protein Vaccine CandidateDe Rosa, S. C., et al. | January 18, 2022We previously described the Phase I-II evaluation of SARS-CoV-2 recombinant protein candidate vaccine, CoV2-PreS-dTM, with…dcorriganJanuary 18, 2022 Read More
Publications of the Week Deep Immune Phenotyping Reveals Similarities between Aging, Down Syndrome, and AutoimmunityLambert, K., et al. | January 13, 2022Individuals with Down syndrome show cellular and clinical features of dysregulated aging of the immune…dcorriganJanuary 13, 2022 Read More